CLEC4C
C-type lectin domain family 4 member C
Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1392187646 | 12:7,882,229 | T/C | — | uncertain significance |
| rs1193664214 | 12:7,882,277 | C/T | — | uncertain significance |
| rs373258524 | 12:7,882,278 | G/A | — | uncertain significance |
| rs199756493 | 12:7,883,406 | T/C | — | uncertain significance |
| rs77889141 | 12:7,890,040 | G/T | — | benign |
| rs761995921 | 12:7,893,499 | C/T | — | — |
| rs150641216 | 12:7,894,023 | T/C | — | uncertain significance |
| rs373679345 | 12:7,894,059 | G/A | — | likely benign |
| rs113848396 | 12:7,894,080 | A/C | — | benign |
| rs934387284 | 12:7,894,083 | T/G | — | uncertain significance |
| rs762441750 | 12:7,894,111 | C/A | — | uncertain significance |
| rs140233014 | 12:7,894,301 | T/A | intron variant | — |
| rs181102230 | 12:7,894,578 | T/C | intron variant | — |
| rs150032474 | 12:7,895,944 | G/T | intron variant | — |
| rs187207576 | 12:7,897,276 | T/C | intron variant | — |
| rs565152331 | 12:7,898,788 | C/T | — | — |
| rs756117278 | 12:7,898,960 | G/T | — | uncertain significance |
| rs370896266 | 12:7,898,972 | C/T | — | uncertain significance |
| rs965136578 | 12:7,899,011 | G/A | — | uncertain significance |
| rs2497426216 | 12:7,899,016 | T/C | — | uncertain significance |
| rs147527087 | 12:7,899,489 | C/T | — | — |
| rs759884664 | 12:7,899,941 | C/T | — | uncertain significance |
| rs7302014 | 12:7,900,994 | T/A | — | — |
| rs189547772 | 12:7,902,636 | G/C | upstream gene variant | — |
| rs11055602 | 12:7,904,111 | T/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.