CLSTN3
calsyntenin 3
Summary
Enables cell-cell adhesion mediator activity and neurexin family protein binding activity. Involved in L-ascorbic acid metabolic process and regulation of synapse assembly. Predicted to be located in several cellular components, including Golgi membrane; dendrite; and postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; lipid droplet; and postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants68 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs144896790 | 12:7,282,149 | C/T | regulatory region variant | — |
| rs2539698022 | 12:7,285,716 | A/G | — | uncertain significance |
| rs373200570 | 12:7,285,728 | C/T | — | uncertain significance |
| rs116872337 | 12:7,285,896 | A/G | upstream gene variant | — |
| rs754859199 | 12:7,286,225 | C/T | — | uncertain significance |
| rs756182506 | 12:7,286,235 | C/T | — | uncertain significance |
| rs141936578 | 12:7,286,236 | G/A | — | likely benign |
| rs150647098 | 12:7,286,267 | C/G | — | uncertain significance |
| rs749951518 | 12:7,286,327 | G/A | — | uncertain significance |
| rs750591063 | 12:7,287,934 | A/T | — | uncertain significance |
| rs1393171977 | 12:7,287,990 | C/T | — | uncertain significance |
| rs142150232 | 12:7,288,041 | G/T | missense variant | — |
| rs370600730 | 12:7,288,101 | C/A | — | uncertain significance |
| rs1939401816 | 12:7,288,406 | T/C | — | association |
| rs7302230 | 12:7,288,432 | A/C | missense variant | — |
| rs137907950 | 12:7,288,440 | G/C | — | uncertain significance |
| rs750239803 | 12:7,288,457 | C/T | — | uncertain significance |
| rs747255044 | 12:7,288,802 | G/T | — | uncertain significance |
| rs537697520 | 12:7,288,836 | T/C | — | benign |
| rs746318546 | 12:7,288,855 | C/T | — | uncertain significance |
| rs150491757 | 12:7,288,970 | C/T | — | uncertain significance |
| rs1336255965 | 12:7,288,975 | C/T | — | uncertain significance |
| rs777008868 | 12:7,289,467 | C/T | — | uncertain significance |
| rs756503676 | 12:7,289,509 | A/G | — | uncertain significance |
| rs200951848 | 12:7,289,657 | C/A | — | uncertain significance |
| rs148348543 | 12:7,289,685 | G/A | — | uncertain significance |
| rs776964256 | 12:7,290,583 | C/T | — | uncertain significance |
| rs781625555 | 12:7,290,614 | C/T | — | uncertain significance |
| rs2305341 | 12:7,293,796 | C/T | — | — |
| rs746506042 | 12:7,293,865 | G/A | — | uncertain significance |
| rs139596561 | 12:7,293,904 | G/A | — | uncertain significance |
| rs2539710325 | 12:7,293,956 | C/T | — | uncertain significance |
| rs1939523253 | 12:7,293,958 | C/T | — | uncertain significance |
| rs781468819 | 12:7,294,708 | G/A | — | uncertain significance |
| rs1393797216 | 12:7,294,728 | C/T | — | likely benign |
| rs150270457 | 12:7,295,495 | A/G | — | uncertain significance |
| rs376009242 | 12:7,295,518 | G/A | — | uncertain significance |
| rs752002614 | 12:7,295,525 | C/T | — | uncertain significance |
| rs138370117 | 12:7,295,814 | C/T | — | uncertain significance |
| rs765368763 | 12:7,295,838 | T/C | — | uncertain significance |
| rs1377179788 | 12:7,295,888 | C/T | — | uncertain significance |
| rs753606577 | 12:7,301,590 | G/A | — | uncertain significance |
| rs764047821 | 12:7,301,705 | A/G | — | uncertain significance |
| rs199814860 | 12:7,301,791 | A/G | — | uncertain significance |
| rs201679632 | 12:7,302,128 | C/A | — | uncertain significance |
| rs145484775 | 12:7,302,172 | A/C | — | uncertain significance |
| rs148818256 | 12:7,302,206 | G/A | — | uncertain significance |
| rs2539722896 | 12:7,303,155 | C/T | — | uncertain significance |
| rs147948411 | 12:7,303,158 | T/C | — | uncertain significance |
| rs1262037075 | 12:7,303,172 | C/A | — | uncertain significance |
| rs372621887 | 12:7,303,202 | G/A | — | uncertain significance |
| rs747617482 | 12:7,303,242 | C/T | — | uncertain significance |
| rs771565220 | 12:7,303,247 | A/G | — | uncertain significance |
| rs147076731 | 12:7,303,548 | C/T | — | uncertain significance |
| rs777195472 | 12:7,303,591 | T/G | — | uncertain significance |
| rs2539723910 | 12:7,303,636 | T/C | — | uncertain significance |
| rs138735435 | 12:7,310,123 | G/A | — | uncertain significance |
| rs1351999372 | 12:7,310,202 | G/A | — | uncertain significance |
| rs2539731772 | 12:7,310,245 | C/G | — | uncertain significance |
| rs117949904 | 12:7,310,306 | C/T | — | benign |
| rs374978104 | 12:7,310,580 | G/C | — | uncertain significance |
| rs146012265 | 12:7,310,610 | C/T | — | uncertain significance |
| rs142128898 | 12:7,310,635 | C/T | — | likely benign |
| rs1290059529 | 12:7,310,638 | C/A | — | uncertain significance |
| rs747649733 | 12:7,310,642 | A/G | — | uncertain significance |
| rs139049762 | 12:7,310,660 | C/T | — | uncertain significance |
| rs771417434 | 12:7,310,666 | C/G | — | uncertain significance |
| rs368460302 | 12:7,310,669 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.