CNTROB

centrobin, centriole duplication and spindle assembly protein

Summary

This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Known Variants72 total

rsidPosition (GRCh37)AllelesClassClinVar
rs74918972817:7,836,434G/C—likely benign
rs75725203717:7,836,435G/A—uncertain significance
rs37250680517:7,836,473G/C—uncertain significance
rs77329881117:7,836,482C/A—uncertain significance
rs77478141217:7,836,489C/T—uncertain significance
rs156790377517:7,836,501C/A—uncertain significance
rs53070739417:7,836,591A/G—uncertain significance
rs197273783717:7,836,596G/A—uncertain significance
rs37754540717:7,836,605G/A—uncertain significance
rs14825348717:7,836,611G/A—uncertain significance
rs77688232617:7,837,493G/A—uncertain significance
rs37676237917:7,837,505A/T—uncertain significance
rs14790015417:7,837,819G/A—uncertain significance
rs14943858917:7,837,861T/C—uncertain significance
rs77936076217:7,838,374T/C—uncertain significance
rs20134248217:7,838,408C/A—uncertain significance
rs103758587917:7,838,673A/C——
rs254530357317:7,839,729C/A—uncertain significance
rs14228056817:7,839,761C/T—likely benign
rs13924069817:7,839,778C/T—likely benign
rs78131915217:7,839,782G/A—uncertain significance
rs57671119517:7,840,029G/A—uncertain significance
rs14542542217:7,840,097C/T—uncertain significance
rs3606472817:7,840,492G/A—uncertain significance
rs14906930617:7,840,531A/G—uncertain significance
rs37199721417:7,840,534G/A—uncertain significance
rs37761370817:7,842,879C/T—uncertain significance
rs76494203217:7,842,904G/A—uncertain significance
rs76951803017:7,842,940G/A—uncertain significance
rs20164989217:7,842,958G/A—likely benign
rs13851145017:7,843,027C/T—uncertain significance
rs20052063517:7,843,040G/T—uncertain significance
rs75601158517:7,843,441G/A—uncertain significance
rs74861783217:7,843,486C/T—uncertain significance
rs137091251317:7,843,516C/G—uncertain significance
rs76007670217:7,846,728G/A—uncertain significance
rs254535639717:7,846,742T/C—uncertain significance
rs75433061817:7,846,782G/A—uncertain significance
rs76196547817:7,847,469C/T—uncertain significance
rs131530792817:7,847,471C/G—uncertain significance
rs75536309017:7,847,518C/T—uncertain significance
rs74949640817:7,847,816G/A—uncertain significance
rs77630400617:7,847,858C/T—uncertain significance
rs15012511317:7,847,918C/A—uncertain significance
rs14549202617:7,847,940C/T—likely benign
rs76902724417:7,849,047C/T—likely benign
rs57685415517:7,849,062C/T—uncertain significance
rs77401275417:7,849,083A/C—uncertain significance
rs78030747817:7,849,111G/T—uncertain significance
rs75361346917:7,849,175G/A—uncertain significance
rs254537279317:7,849,203G/T—uncertain significance
rs19002902717:7,849,220C/G—uncertain significance
rs75774412417:7,849,299C/A—uncertain significance
rs197469779317:7,850,917C/G—uncertain significance
rs7626278317:7,850,972G/A—uncertain significance
rs7459564917:7,851,278C/T—likely benign
rs37737852117:7,851,288C/G—uncertain significance
rs37754798917:7,851,529C/T—uncertain significance
rs37047487217:7,851,579C/T—uncertain significance
rs103075185217:7,851,589A/C—uncertain significance
rs55113944417:7,851,873C/T—uncertain significance
rs20127979717:7,851,924C/G—uncertain significance
rs56390870917:7,851,935C/G—uncertain significance
rs75836598017:7,851,991G/A—uncertain significance
rs77222305217:7,852,721C/T—uncertain significance
rs75432378517:7,852,725G/A—uncertain significance
rs14015828317:7,852,727C/T—uncertain significance
rs53826637417:7,852,728G/A—uncertain significance
rs53063784917:7,852,762C/T—likely benign
rs37138306217:7,852,767G/A—uncertain significance
rs155563092917:7,852,808C/T—uncertain significance
rs75713902917:7,852,815G/A—uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.