CPB1
carboxypeptidase B1
Summary
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs80013498 | 3:148,545,789 | C/T | — | benign |
| rs754000895 | 3:148,545,812 | T/C | — | uncertain significance |
| rs114058679 | 3:148,545,841 | C/T | — | uncertain significance |
| rs193238667 | 3:148,545,842 | G/A | — | benign |
| rs146944241 | 3:148,552,329 | C/T | — | likely benign |
| rs146504027 | 3:148,552,330 | A/G | — | likely benign |
| rs199961136 | 3:148,552,346 | G/A | — | likely benign |
| rs1005527114 | 3:148,552,361 | A/G | — | uncertain significance |
| rs377287962 | 3:148,558,682 | G/C | — | uncertain significance |
| rs189467346 | 3:148,558,684 | C/T | — | likely benign |
| rs138120056 | 3:148,559,651 | A/C | — | benign |
| rs375559471 | 3:148,559,706 | A/G | — | uncertain significance |
| rs1713172797 | 3:148,562,265 | G/T | — | uncertain significance |
| rs759210795 | 3:148,562,271 | C/T | — | uncertain significance |
| rs145346983 | 3:148,562,272 | A/G | — | benign |
| rs147755306 | 3:148,562,309 | C/T | — | benign |
| rs1059502 | 3:148,562,310 | G/A | — | benign |
| rs770424800 | 3:148,562,381 | T/C | — | likely benign |
| rs13318851 | 3:148,562,397 | G/C | intron variant | — |
| rs13318853 | 3:148,562,399 | G/A | intron variant | — |
| rs73866671 | 3:148,562,470 | T/C | — | benign |
| rs761703950 | 3:148,562,485 | C/T | — | uncertain significance |
| rs2472892287 | 3:148,562,521 | G/A | — | uncertain significance |
| rs146324474 | 3:148,562,540 | A/G | — | uncertain significance |
| rs76950051 | 3:148,562,560 | T/C | — | benign |
| rs925299154 | 3:148,563,226 | G/A | — | likely benign |
| rs775948112 | 3:148,563,249 | T/C | — | uncertain significance |
| rs780914999 | 3:148,563,280 | C/G | — | uncertain significance |
| rs1226704681 | 3:148,563,412 | T/G | — | uncertain significance |
| rs147578743 | 3:148,575,289 | G/A | — | uncertain significance |
| rs751289522 | 3:148,577,607 | G/A | — | uncertain significance |
| rs144356818 | 3:148,577,674 | G/A | — | uncertain significance |
| rs61733983 | 3:148,577,717 | C/G | — | benign |
| rs1246215694 | 3:148,577,719 | G/A | — | likely benign |
| rs148833513 | 3:148,577,730 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.