CREB5
cAMP responsive element binding protein 5
Summary
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Known Variants40 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11765845 | 7:28,391,142 | A/G | intron variant | — |
| rs7779602 | 7:28,392,168 | T/A | intron variant | — |
| rs7805378 | 7:28,393,403 | A/C | intron variant | — |
| rs7782838 | 7:28,411,649 | G/A | — | — |
| rs7782844 | 7:28,411,654 | G/C | — | — |
| rs12535186 | 7:28,414,188 | G/A | intron variant | — |
| rs6462079 | 7:28,415,827 | G/A | intron variant | — |
| rs9639577 | 7:28,417,544 | C/A | intron variant | — |
| rs7799265 | 7:28,432,476 | C/T | — | — |
| rs42708 | 7:28,445,612 | G/A | regulatory region variant | — |
| rs4722804 | 7:28,532,464 | T/G | — | association |
| rs754986749 | 7:28,534,524 | C/T | — | uncertain significance |
| rs10258092 | 7:28,547,607 | T/C | regulatory region variant | — |
| rs177592 | 7:28,559,785 | G/C | intron variant | — |
| rs751259024 | 7:28,609,990 | C/T | — | uncertain significance |
| rs114327290 | 7:28,610,020 | C/T | — | uncertain significance |
| rs143789664 | 7:28,610,028 | G/A | — | uncertain significance |
| rs2535437886 | 7:28,610,056 | T/A | — | uncertain significance |
| rs1338736806 | 7:28,610,063 | C/G | — | uncertain significance |
| rs2535438211 | 7:28,610,104 | C/T | — | uncertain significance |
| rs367885203 | 7:28,610,112 | A/T | — | uncertain significance |
| rs374897586 | 7:28,610,145 | C/T | — | uncertain significance |
| rs33998128 | 7:28,636,927 | C/G | — | — |
| rs75604893 | 7:28,725,433 | G/A | regulatory region variant | — |
| rs2237349 | 7:28,762,963 | C/T | intron variant | — |
| rs368604817 | 7:28,763,846 | G/A | — | uncertain significance |
| rs1803211251 | 7:28,763,909 | C/A | — | uncertain significance |
| rs1233628355 | 7:28,763,929 | A/G | — | uncertain significance |
| rs10238623 | 7:28,812,493 | A/G | intron variant | — |
| rs747120884 | 7:28,843,867 | A/G | — | uncertain significance |
| rs201838146 | 7:28,843,898 | T/C | — | uncertain significance |
| rs561182352 | 7:28,843,907 | G/A | — | uncertain significance |
| rs754550142 | 7:28,843,946 | C/T | — | uncertain significance |
| rs377537383 | 7:28,844,003 | C/T | — | uncertain significance |
| rs759449695 | 7:28,844,020 | C/A | — | uncertain significance |
| rs2535037106 | 7:28,848,867 | G/T | — | uncertain significance |
| rs376502932 | 7:28,848,874 | G/T | — | uncertain significance |
| rs781328727 | 7:28,848,969 | G/T | — | uncertain significance |
| rs115644935 | 7:28,857,728 | A/G | — | uncertain significance |
| rs759707007 | 7:28,858,831 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.