CRTAM
cytotoxic and regulatory T cell molecule
Summary
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]
Known Variants24 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11218857 | 11:122,708,467 | A/G | — | — |
| rs759312696 | 11:122,709,263 | G/T | — | uncertain significance |
| rs376210389 | 11:122,709,268 | T/A | — | uncertain significance |
| rs184845740 | 11:122,718,869 | A/G | intron variant | — |
| rs35411582 | 11:122,720,776 | A/C | — | benign |
| rs2539684053 | 11:122,720,915 | G/C | — | uncertain significance |
| rs34397316 | 11:122,722,440 | C/A | — | benign |
| rs1349327784 | 11:122,722,514 | G/A | — | likely benign |
| rs56388952 | 11:122,724,745 | G/A | — | benign |
| rs35136295 | 11:122,726,430 | A/G | — | benign |
| rs529604921 | 11:122,726,454 | G/A | — | uncertain significance |
| rs147423411 | 11:122,726,490 | C/T | — | uncertain significance |
| rs35561350 | 11:122,726,491 | G/A | — | benign |
| rs139060588 | 11:122,735,344 | T/C | — | uncertain significance |
| rs75065751 | 11:122,735,368 | C/T | — | benign |
| rs759987502 | 11:122,735,385 | G/A | — | uncertain significance |
| rs10892918 | 11:122,736,207 | G/C | — | — |
| rs750458554 | 11:122,738,123 | A/G | — | uncertain significance |
| rs1862191667 | 11:122,738,129 | A/G | — | uncertain significance |
| rs199677419 | 11:122,738,225 | T/C | — | uncertain significance |
| rs2272094 | 11:122,738,261 | A/G | missense variant | — |
| rs148256561 | 11:122,738,726 | G/A | — | uncertain significance |
| rs762806413 | 11:122,742,004 | A/G | — | uncertain significance |
| rs142339889 | 11:122,742,051 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.