CTDSPL

CTD small phosphatase like

Summary

Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of G1/S transition of mitotic cell cycle and negative regulation of protein phosphorylation. Located in extracellular exosome. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Apr 2025]

Known Variants15 total

rsidPosition (GRCh37)AllelesClassClinVar
rs9995422783:37,903,697G/Tuncertain significance
rs9985502283:37,903,706A/Guncertain significance
rs773883653:37,962,472G/Cintron variant
rs24708655933:37,988,605T/Cuncertain significance
rs5562596803:37,992,722G/A
rs67919463:37,993,376T/Gintron variant
rs93111713:37,996,477T/Gintron variant
rs7545617003:37,998,617G/Auncertain significance
rs1918301753:37,998,633G/Auncertain significance
rs1511891623:38,006,068G/Auncertain significance
rs12408482823:38,006,156C/Tuncertain significance
rs73722093:38,010,708T/G
rs24709064093:38,017,263G/Cuncertain significance
rs7565226383:38,022,312G/Auncertain significance
rs7459889933:38,022,320G/Auncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.