CTF1

cardiotrophin 1

Summary

The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Known Variants143 total

rsidPosition (GRCh37)AllelesClassClinVar
rs39751664716:30,907,995G/C—uncertain significance
rs1186296216:30,909,706C/G—benign
rs98555458616:30,910,719C/T—likely benign
rs214323315916:30,910,721C/T—likely benign
rs20072986516:30,910,723C/T—likely benign
rs72750294816:30,910,724C/G—conflicting classifications of pathogenicity
rs130383892716:30,910,735G/A—uncertain significance
rs205538203416:30,910,736A/C—uncertain significance
rs104329129616:30,910,742C/G—uncertain significance
rs36991778116:30,910,744C/T—uncertain significance
rs214323338916:30,910,747A/G—uncertain significance
rs54407346916:30,910,765C/A—likely benign
rs254373534316:30,910,774C/G—uncertain significance
rs75983140716:30,910,785C/A—likely benign
rs20170354716:30,910,793G/A—conflicting classifications of pathogenicity
rs75613562516:30,910,801C/T—uncertain significance
rs75395641816:30,910,811C/T—uncertain significance
rs72750483716:30,910,812G/A—likely benign
rs77108033416:30,910,813C/A—uncertain significance
rs19218407116:30,910,821C/T—likely benign
rs805926916:30,910,830C/T—benign
rs14934249416:30,910,831G/T—conflicting classifications of pathogenicity
rs124321387916:30,910,840C/G—uncertain significance
rs37435936516:30,910,861G/T—likely benign
rs11815191716:30,913,195G/C—likely benign
rs39751664616:30,913,386C/T—conflicting classifications of pathogenicity
rs39751664516:30,913,389G/A—conflicting classifications of pathogenicity
rs78100494616:30,913,392T/A—uncertain significance
rs74762646816:30,913,412G/A—uncertain significance
rs137071479416:30,913,416C/A—uncertain significance
rs119421898916:30,913,426C/T—likely benign
rs126965244516:30,913,428G/A—likely benign
rs89994735316:30,913,437C/A—uncertain significance
rs214324427016:30,913,438T/A—uncertain significance
rs137363508716:30,913,444C/T—conflicting classifications of pathogenicity
rs140520425616:30,913,455G/T—likely benign
rs156733119116:30,913,461C/A—likely benign
rs205540605916:30,913,462G/A—uncertain significance
rs100135508116:30,913,465C/A—uncertain significance
rs125266996916:30,913,473C/G—likely benign
rs138545823616:30,913,478C/T—uncertain significance
rs88605192316:30,913,482G/A—likely benign
rs254374022316:30,913,489G/A—uncertain significance
rs142151126716:30,913,492G/A—uncertain significance
rs214324482016:30,913,500A/C—likely benign
rs121674138416:30,913,504C/T—uncertain significance
rs145282015116:30,913,506C/G—uncertain significance
rs148920813316:30,913,507G/A—uncertain significance
rs121555478916:30,913,517G/T—uncertain significance
rs223493316:30,913,528G/A—conflicting classifications of pathogenicity
rs72750294916:30,913,529C/A—conflicting classifications of pathogenicity
rs39751664816:30,913,534C/T—likely benign
rs254374039616:30,913,539C/T—likely benign
rs97419615816:30,913,541C/A—uncertain significance
rs205540771816:30,913,545G/T—likely benign
rs135108652416:30,913,546C/G—uncertain significance
rs156733127916:30,913,547C/T—uncertain significance
rs205540793016:30,913,549C/G—uncertain significance
rs205540796216:30,913,550C/T—uncertain significance
rs148979537216:30,913,558G/C—uncertain significance
rs254374048816:30,913,560C/T—likely benign
rs136741578916:30,913,565T/C—uncertain significance
rs132479007116:30,913,568G/A—uncertain significance
rs119319164116:30,913,570C/T—uncertain significance
rs72750295016:30,913,573C/T—uncertain significance
rs139175963416:30,913,582G/A—uncertain significance
rs142786652716:30,913,586T/C—uncertain significance
rs205540857416:30,913,591C/A—uncertain significance
rs39751664916:30,913,595G/A—likely benign
rs119276002516:30,913,596C/A—likely benign
rs88605192416:30,913,601C/G—uncertain significance
rs133206437616:30,913,604G/A—uncertain significance
rs205540923316:30,913,610T/G—uncertain significance
rs205540927116:30,913,612C/T—uncertain significance
rs142479213916:30,913,617C/A—likely benign
rs138472276516:30,913,618C/G—uncertain significance
rs214324624516:30,913,626C/G—uncertain significance
rs116251332816:30,913,631C/G—uncertain significance
rs98242603116:30,913,640C/T—uncertain significance
rs91284606416:30,913,642C/G—uncertain significance
rs205540969016:30,913,643G/A—uncertain significance
rs254374093816:30,913,645G/A—uncertain significance
rs159663969316:30,913,653C/A—likely benign
rs129414053016:30,913,656C/T—likely benign
rs254374105816:30,913,667C/A—uncertain significance
rs72750512116:30,913,668C/A—likely benign
rs254374110616:30,913,674G/T—likely benign
rs132006566516:30,913,680G/T—likely benign
rs254374116616:30,913,683G/A—likely benign
rs76921761116:30,913,697G/T—uncertain significance
rs131782467216:30,913,701G/T—likely benign
rs146727547116:30,913,708G/C—conflicting classifications of pathogenicity
rs144841953916:30,913,710C/T—likely benign
rs136022777716:30,913,711G/A—uncertain significance
rs205541101216:30,913,714C/T—uncertain significance
rs77942609116:30,913,718C/A—uncertain significance
rs89995829916:30,913,719C/A—likely benign
rs93677529816:30,913,720G/A—uncertain significance
rs39751665016:30,913,722C/T—likely benign
rs87665776816:30,913,723G/A—uncertain significance

Showing 100 of 143 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.