CXCL9
C-X-C motif chemokine ligand 9
Summary
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded is thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils. [provided by RefSeq, Aug 2020]
Known Variants16 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs10336 | 4:76,922,988 | A/G | 3 prime UTR variant | — |
| rs3733236 | 4:76,923,998 | G/A | 3 prime UTR variant | — |
| rs138184008 | 4:76,924,754 | T/C | — | benign |
| rs139830877 | 4:76,924,788 | C/T | — | uncertain significance |
| rs1731522906 | 4:76,924,818 | T/G | — | uncertain significance |
| rs1560567256 | 4:76,924,839 | T/G | — | uncertain significance |
| rs769576198 | 4:76,926,002 | G/A | — | uncertain significance |
| rs890060522 | 4:76,926,029 | C/G | — | uncertain significance |
| rs1038530014 | 4:76,927,317 | C/T | — | uncertain significance |
| rs773967412 | 4:76,927,338 | A/C | — | uncertain significance |
| rs145442311 | 4:76,927,373 | G/C | — | likely benign |
| rs1008012650 | 4:76,927,389 | T/C | — | uncertain significance |
| rs771431360 | 4:76,927,418 | A/G | — | uncertain significance |
| rs2276886 | 4:76,928,428 | C/T | regulatory region variant | — |
| rs2476512892 | 4:76,928,571 | C/T | — | uncertain significance |
| rs190949856 | 4:76,930,244 | C/T | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.