CYP4Z1
cytochrome P450 family 4 subfamily Z member 1
Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33. [provided by RefSeq, Jul 2008]
Known Variants34 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs763125700 | 1:47,533,173 | C/G | — | uncertain significance |
| rs754400619 | 1:47,533,200 | C/G | — | uncertain significance |
| rs746529579 | 1:47,533,226 | A/C | — | likely benign |
| rs2522282271 | 1:47,533,274 | T/C | — | likely benign |
| rs35562865 | 1:47,533,511 | G/A | intron variant | — |
| rs373456415 | 1:47,534,412 | C/T | — | uncertain significance |
| rs1413639367 | 1:47,548,105 | T/C | — | uncertain significance |
| rs368708579 | 1:47,548,123 | G/A | — | uncertain significance |
| rs775025928 | 1:47,550,307 | C/A | — | uncertain significance |
| rs375028977 | 1:47,550,325 | C/T | — | likely benign |
| rs766245765 | 1:47,550,331 | G/A | — | uncertain significance |
| rs2522332790 | 1:47,550,357 | G/A | — | uncertain significance |
| rs753024597 | 1:47,550,374 | T/C | — | uncertain significance |
| rs758670291 | 1:47,550,377 | A/G | — | uncertain significance |
| rs2522333037 | 1:47,550,415 | A/T | — | uncertain significance |
| rs147199588 | 1:47,550,551 | C/A | — | uncertain significance |
| rs745842351 | 1:47,550,569 | C/T | — | uncertain significance |
| rs756562508 | 1:47,550,624 | T/C | — | uncertain significance |
| rs757902695 | 1:47,560,255 | C/T | — | uncertain significance |
| rs748235991 | 1:47,560,306 | C/T | — | uncertain significance |
| rs146391078 | 1:47,560,307 | G/A | — | benign |
| rs575780043 | 1:47,560,333 | A/C | — | uncertain significance |
| rs531653571 | 1:47,564,768 | C/T | — | likely benign |
| rs6690005 | 1:47,571,391 | G/A | — | association |
| rs760900078 | 1:47,571,825 | A/G | — | uncertain significance |
| rs2522405620 | 1:47,571,838 | T/C | — | uncertain significance |
| rs761531357 | 1:47,571,878 | A/G | — | uncertain significance |
| rs201816403 | 1:47,571,882 | C/T | — | uncertain significance |
| rs766602882 | 1:47,571,891 | G/A | — | uncertain significance |
| rs144526298 | 1:47,571,918 | C/T | — | uncertain significance |
| rs2522430814 | 1:47,581,261 | C/G | — | uncertain significance |
| rs550113245 | 1:47,582,383 | T/C | — | uncertain significance |
| rs2148544712 | 1:47,583,455 | A/G | — | uncertain significance |
| rs754935445 | 1:47,583,478 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.