DAPK2
death associated protein kinase 2
Summary
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
Known Variants37 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs113007196 | 15:64,200,734 | C/T | — | benign |
| rs2504929514 | 15:64,200,777 | T/A | — | uncertain significance |
| rs2504929643 | 15:64,200,790 | C/T | — | uncertain significance |
| rs140149939 | 15:64,204,133 | C/T | — | uncertain significance |
| rs200773863 | 15:64,204,147 | G/C | — | uncertain significance |
| rs2504956538 | 15:64,204,166 | A/G | — | uncertain significance |
| rs2504956611 | 15:64,204,171 | G/T | — | uncertain significance |
| rs761122652 | 15:64,204,315 | G/A | — | uncertain significance |
| rs776636585 | 15:64,204,321 | G/A | — | uncertain significance |
| rs761897052 | 15:64,204,324 | C/T | — | uncertain significance |
| rs149186606 | 15:64,204,394 | C/T | — | benign |
| rs1258428061 | 15:64,217,026 | G/A | — | uncertain significance |
| rs145658373 | 15:64,217,055 | C/T | — | uncertain significance |
| rs34270163 | 15:64,218,141 | G/A | — | uncertain significance |
| rs34104782 | 15:64,218,142 | G/A | — | benign |
| rs2505021436 | 15:64,218,173 | T/A | — | uncertain significance |
| rs374682269 | 15:64,218,184 | C/G | — | uncertain significance |
| rs200851607 | 15:64,218,285 | C/T | — | uncertain significance |
| rs200278398 | 15:64,222,598 | C/A | — | likely benign |
| rs2140742723 | 15:64,263,624 | T/G | — | uncertain significance |
| rs555303465 | 15:64,263,651 | T/G | — | uncertain significance |
| rs147197384 | 15:64,263,670 | A/C | — | uncertain significance |
| rs866675633 | 15:64,263,698 | G/A | — | uncertain significance |
| rs553988389 | 15:64,263,738 | C/T | — | uncertain significance |
| rs55986634 | 15:64,275,645 | G/C | — | — |
| rs201432861 | 15:64,275,759 | C/T | — | uncertain significance |
| rs142526378 | 15:64,275,763 | T/C | — | uncertain significance |
| rs117564318 | 15:64,275,843 | C/T | — | likely benign |
| rs922516659 | 15:64,275,858 | C/T | — | uncertain significance |
| rs62639966 | 15:64,275,866 | C/T | — | likely benign |
| rs145090475 | 15:64,275,867 | C/T | — | likely benign |
| rs773075712 | 15:64,275,877 | G/A | — | uncertain significance |
| rs201545659 | 15:64,275,912 | G/A | — | uncertain significance |
| rs145891572 | 15:64,275,924 | C/T | — | uncertain significance |
| rs779268346 | 15:64,275,925 | G/A | — | uncertain significance |
| rs770946548 | 15:64,275,937 | C/T | — | uncertain significance |
| rs547035765 | 15:64,275,945 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.