DBF4
DBF4-CDC7 kinase regulatory subunit
Summary
Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants31 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs34483317 | 7:87,507,375 | C/A | — | benign |
| rs576459063 | 7:87,507,397 | A/G | — | uncertain significance |
| rs2535334613 | 7:87,507,462 | G/C | — | uncertain significance |
| rs183784927 | 7:87,508,340 | C/T | upstream gene variant | — |
| rs79425419 | 7:87,518,947 | C/T | intron variant | — |
| rs758677398 | 7:87,525,808 | G/A | — | uncertain significance |
| rs117960773 | 7:87,527,061 | G/A | intron variant | — |
| rs552496933 | 7:87,528,683 | T/C | — | — |
| rs2535379037 | 7:87,529,617 | T/G | — | uncertain significance |
| rs1473447497 | 7:87,529,622 | A/T | — | uncertain significance |
| rs1003386108 | 7:87,533,632 | A/G | — | uncertain significance |
| rs1675139590 | 7:87,536,525 | C/T | — | uncertain significance |
| rs780933871 | 7:87,536,556 | A/G | — | uncertain significance |
| rs146586322 | 7:87,536,615 | G/C | — | uncertain significance |
| rs775030398 | 7:87,536,703 | C/G | — | uncertain significance |
| rs761147230 | 7:87,536,705 | C/G | — | uncertain significance |
| rs751644133 | 7:87,536,769 | C/T | — | uncertain significance |
| rs2535394518 | 7:87,537,009 | A/C | — | uncertain significance |
| rs138055219 | 7:87,537,029 | A/G | — | benign |
| rs771071260 | 7:87,537,036 | C/T | — | uncertain significance |
| rs376221180 | 7:87,537,038 | C/T | — | uncertain significance |
| rs2535394625 | 7:87,537,055 | A/G | — | uncertain significance |
| rs572985082 | 7:87,537,071 | C/A | — | uncertain significance |
| rs1226153710 | 7:87,537,111 | C/T | — | uncertain significance |
| rs2131082159 | 7:87,537,125 | C/T | — | uncertain significance |
| rs1414701678 | 7:87,537,180 | G/A | — | uncertain significance |
| rs61747462 | 7:87,537,188 | A/G | — | benign |
| rs193054147 | 7:87,537,276 | A/G | — | uncertain significance |
| rs527402949 | 7:87,537,413 | A/G | — | uncertain significance |
| rs774223748 | 7:87,537,435 | C/T | — | uncertain significance |
| rs368286595 | 7:87,537,444 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.