DCHS1

dachsous cadherin-related 1

Summary

This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. [provided by RefSeq, Jul 2008]

Known Variants1,643 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs77307773	11:6,642,835	C/T	—	likely benign
rs765591706	11:6,643,022	C/G	—	uncertain significance
rs773543020	11:6,643,024	C/G	—	uncertain significance
rs763186035	11:6,643,025	C/T	—	likely benign
rs761356492	11:6,643,026	G/A	—	uncertain significance
rs965617510	11:6,643,028	G/A	—	likely benign
rs751883574	11:6,643,037	T/C	—	likely benign
rs2493807239	11:6,643,041	T/A	—	uncertain significance
rs1855695634	11:6,643,048	C/A	—	uncertain significance
rs146383176	11:6,643,057	C/T	—	likely benign
rs148587402	11:6,643,058	G/A	—	likely benign
rs758033350	11:6,643,063	G/C	—	uncertain significance
rs1192783882	11:6,643,066	C/A	—	uncertain significance
rs1025982647	11:6,643,068	G/A	—	uncertain significance
rs201436786	11:6,643,073	T/C	—	likely benign
rs770014749	11:6,643,083	T/C	—	uncertain significance
rs141839556	11:6,643,103	G/A	—	likely benign
rs530939498	11:6,643,108	C/T	—	uncertain significance
rs774638070	11:6,643,109	G/A	—	likely benign
rs61735331	11:6,643,110	G/A	—	conflicting classifications of pathogenicity
rs768054914	11:6,643,113	G/A	—	uncertain significance
rs753181516	11:6,643,116	C/T	—	uncertain significance
rs200963531	11:6,643,117	G/A	—	uncertain significance
rs139763043	11:6,643,120	C/T	—	uncertain significance
rs2493807457	11:6,643,135	G/A	—	likely benign
rs1855697810	11:6,643,137	G/C	—	uncertain significance
rs749886693	11:6,643,141	G/A	—	uncertain significance
rs2493807482	11:6,643,145	G/A	—	likely benign
rs758004006	11:6,643,148	G/C	—	uncertain significance
rs1252382052	11:6,643,158	A/G	—	uncertain significance
rs368150563	11:6,643,159	T/G	—	uncertain significance
rs1855698493	11:6,643,161	G/A	—	uncertain significance
rs188298100	11:6,643,162	C/G	—	uncertain significance
rs180772321	11:6,643,163	A/G	—	likely benign
rs371058396	11:6,643,172	C/G	—	likely benign
rs778012430	11:6,643,179	C/G	—	uncertain significance
rs1484537905	11:6,643,189	T/G	—	uncertain significance
rs774601128	11:6,643,194	G/C	—	uncertain significance
rs2493807638	11:6,643,196	G/A	—	likely benign
rs2493807645	11:6,643,198	A/G	—	uncertain significance
rs1418163020	11:6,643,200	C/T	—	uncertain significance
rs772450059	11:6,643,201	G/A	—	uncertain significance
rs1855699874	11:6,643,202	G/A	—	likely benign
rs2493807655	11:6,643,203	T/G	—	uncertain significance
rs942214212	11:6,643,206	G/A	—	uncertain significance
rs761179038	11:6,643,213	G/C	—	uncertain significance
rs764531485	11:6,643,222	T/C	—	uncertain significance
rs1855700212	11:6,643,224	G/A	—	uncertain significance
rs374331068	11:6,643,227	C/T	—	uncertain significance
rs547000377	11:6,643,228	G/A	—	uncertain significance
rs754635337	11:6,643,233	G/T	—	uncertain significance
rs2493807741	11:6,643,243	T/C	—	uncertain significance
rs993900360	11:6,643,246	C/T	—	uncertain significance
rs1394619129	11:6,643,254	G/T	—	uncertain significance
rs752482712	11:6,643,259	C/T	—	likely benign
rs1855701301	11:6,643,264	A/T	—	uncertain significance
rs777763269	11:6,643,265	C/T	—	likely benign
rs749367746	11:6,643,268	G/C	—	likely benign
rs1589951196	11:6,643,278	T/A	—	uncertain significance
rs1855702144	11:6,643,286	G/A	—	likely benign
rs2493807860	11:6,643,288	C/A	—	uncertain significance
rs200088487	11:6,643,290	G/A	—	uncertain significance
rs143630838	11:6,643,298	G/C	—	likely benign
rs769187993	11:6,643,310	G/A	—	likely benign
rs777169716	11:6,643,312	T/C	—	uncertain significance
rs139629352	11:6,643,314	C/T	—	uncertain significance
rs779065285	11:6,643,315	G/A	—	uncertain significance
rs2493807940	11:6,643,316	G/A	—	likely benign
rs2493807967	11:6,643,327	G/A	—	uncertain significance
rs145246077	11:6,643,346	C/T	—	likely benign
rs372218018	11:6,643,349	G/C	—	likely benign
rs779058249	11:6,643,353	C/T	—	uncertain significance
rs745894081	11:6,643,354	G/A	—	uncertain significance
rs1236669312	11:6,643,358	G/A	—	likely benign
rs979852727	11:6,643,374	C/T	—	uncertain significance
rs2493808117	11:6,643,392	T/A	—	uncertain significance
rs775835626	11:6,643,394	A/G	—	benign
rs770139460	11:6,643,398	C/G	—	uncertain significance
rs1855704818	11:6,643,401	C/T	—	uncertain significance
rs928281168	11:6,643,417	C/A	—	uncertain significance
rs767319271	11:6,643,425	T/G	—	uncertain significance
rs775261458	11:6,643,430	G/A	—	likely benign
rs760356441	11:6,643,434	C/T	—	uncertain significance
rs145042783	11:6,643,448	G/A	—	likely benign
rs752799248	11:6,643,450	C/T	—	uncertain significance
rs1195662828	11:6,643,458	A/G	—	uncertain significance
rs1253004897	11:6,643,459	T/C	—	uncertain significance
rs2134606689	11:6,643,464	G/A	—	uncertain significance
rs755085535	11:6,643,466	C/T	—	likely benign
rs1298648060	11:6,643,471	C/A	—	uncertain significance
rs771730718	11:6,643,473	C/T	—	uncertain significance
rs919429958	11:6,643,477	C/T	—	uncertain significance
rs1855706972	11:6,643,483	A/G	—	uncertain significance
rs766624649	11:6,643,485	G/A	—	uncertain significance
rs2134606797	11:6,643,487	C/T	—	likely benign
rs760382120	11:6,643,489	T/G	—	uncertain significance
rs768138201	11:6,643,490	G/C	—	likely benign
rs761513230	11:6,643,496	T/A	—	likely benign
rs1259764789	11:6,643,499	T/C	—	likely benign
rs766449407	11:6,643,502	G/A	—	likely benign

Showing 100 of 1,643 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.