DCSTAMP
dendrocyte expressed seven transmembrane protein
Summary
This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Known Variants27 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2458413 | 8:105,359,432 | C/T | intron variant | — |
| rs1564065237 | 8:105,360,784 | G/C | — | uncertain significance |
| rs201921514 | 8:105,360,904 | A/C | — | uncertain significance |
| rs368756833 | 8:105,360,975 | G/T | — | uncertain significance |
| rs143444954 | 8:105,360,983 | C/A | — | uncertain significance |
| rs771611522 | 8:105,361,001 | G/T | — | uncertain significance |
| rs2537629059 | 8:105,361,006 | A/G | — | uncertain significance |
| rs1432223419 | 8:105,361,090 | G/A | — | uncertain significance |
| rs200594066 | 8:105,361,096 | G/A | — | uncertain significance |
| rs1810387151 | 8:105,361,142 | T/G | — | uncertain significance |
| rs758100898 | 8:105,361,190 | A/G | — | uncertain significance |
| rs779366450 | 8:105,361,334 | A/G | — | uncertain significance |
| rs769902138 | 8:105,361,366 | G/A | — | likely benign |
| rs905159606 | 8:105,361,405 | T/C | — | uncertain significance |
| rs2537630303 | 8:105,361,517 | A/G | — | uncertain significance |
| rs146710492 | 8:105,361,634 | C/T | — | likely benign |
| rs150312993 | 8:105,361,724 | A/T | — | uncertain significance |
| rs368380124 | 8:105,361,748 | C/T | — | uncertain significance |
| rs539294681 | 8:105,367,109 | A/C | — | uncertain significance |
| rs3802204 | 8:105,367,121 | G/A | — | benign |
| rs1810573677 | 8:105,367,122 | T/A | — | uncertain significance |
| rs200236161 | 8:105,367,185 | A/C | — | uncertain significance |
| rs372537268 | 8:105,367,223 | T/C | — | uncertain significance |
| rs62620995 | 8:105,367,264 | C/T | missense variant | — |
| rs200921068 | 8:105,367,309 | G/A | — | likely benign |
| rs761743706 | 8:105,367,397 | G/C | — | uncertain significance |
| rs2537638793 | 8:105,368,360 | C/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.