DDIAS

DNA damage induced apoptosis suppressor

Summary

Involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and regulation of DNA stability. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants43 total

rsidPosition (GRCh37)AllelesClassClinVar
rs7759993411:82,617,917A/Gintron variant—
rs1123337111:82,623,337T/Cintron variant—
rs14288387211:82,625,788G/A—uncertain significance
rs249581716211:82,625,869C/G—uncertain significance
rs102457996511:82,625,876A/G—uncertain significance
rs77517251811:82,625,883G/A—uncertain significance
rs14512006011:82,641,233C/A—uncertain significance
rs186095400611:82,641,239A/G—uncertain significance
rs75791772611:82,641,252A/G—uncertain significance
rs20148085711:82,641,264C/G—uncertain significance
rs186099027311:82,642,781A/G—uncertain significance
rs249585563311:82,642,818C/A—uncertain significance
rs14064463611:82,642,894A/G—likely benign
rs37536625611:82,642,948T/A—uncertain significance
rs136398270511:82,643,004T/A—likely benign
rs126064520311:82,643,017G/C—uncertain significance
rs121373471111:82,643,041G/A—uncertain significance
rs37334690911:82,643,113T/C—likely benign
rs53213556911:82,643,273T/C—uncertain significance
rs133083112411:82,643,357A/C—uncertain significance
rs249585939411:82,643,545G/T—uncertain significance
rs76869729211:82,643,726A/C—uncertain significance
rs249586046311:82,643,759G/A—uncertain significance
rs186102752311:82,643,848T/A—likely benign
rs14448974311:82,643,932G/C—uncertain significance
rs14534145011:82,644,078G/C—uncertain significance
rs141598540911:82,644,350T/C—uncertain significance
rs77469535211:82,644,361G/A—likely benign
rs14703686511:82,644,379A/G—uncertain significance
rs249586379211:82,644,386A/G—uncertain significance
rs20167176011:82,644,445A/G—uncertain significance
rs77342878311:82,644,523G/A—uncertain significance
rs249586489811:82,644,590A/G—uncertain significance
rs148057512511:82,644,608G/A—uncertain significance
rs20115123911:82,644,611A/C—uncertain significance
rs76088584311:82,644,626C/T—uncertain significance
rs249586533911:82,644,674G/C—uncertain significance
rs14930635111:82,644,709A/G—likely benign
rs37735238111:82,644,841C/T—uncertain significance
rs20067561711:82,644,892A/G—likely benign
rs15070047611:82,645,015G/C—uncertain significance
rs75395240211:82,645,172A/G—uncertain significance
rs140757291311:82,645,328C/T—uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.