DGKZ

diacylglycerol kinase zeta

Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

Known Variants347 total

rsidPosition (GRCh37)AllelesClassClinVar
rs120260592811:46,354,905G/A—uncertain significance
rs141544625911:46,354,925G/A—uncertain significance
rs249621504111:46,354,926A/T—uncertain significance
rs94468472411:46,354,991G/A—uncertain significance
rs249621557811:46,355,003C/G—uncertain significance
rs76172857211:46,355,007A/G—uncertain significance
rs123168689711:46,369,224C/T—likely benign
rs118768306211:46,369,296C/T—likely benign
rs1103887111:46,379,442T/G——
rs37621298411:46,387,834C/T—uncertain significance
rs14315508711:46,387,835G/A—benign
rs143719213811:46,387,838G/A—uncertain significance
rs19146211311:46,387,843G/A—uncertain significance
rs20074685911:46,387,852C/G—benign
rs146663698611:46,387,860G/A—likely benign
rs124156863311:46,387,864C/T—uncertain significance
rs131782611:46,387,868A/G—benign
rs53435769711:46,387,870C/T—uncertain significance
rs76107576611:46,387,871G/A—uncertain significance
rs1182079111:46,387,883T/C—benign
rs37605290811:46,387,906C/T—likely benign
rs74940515511:46,387,907G/A—uncertain significance
rs36966881411:46,387,909C/A—uncertain significance
rs37745129311:46,387,910G/A—uncertain significance
rs77571583311:46,387,912C/T—uncertain significance
rs76104055511:46,387,913G/A—uncertain significance
rs76452934011:46,387,916C/A—uncertain significance
rs37354747711:46,387,917C/G—likely benign
rs11662753311:46,387,920C/T—likely benign
rs76258692311:46,387,921G/A—uncertain significance
rs75132754811:46,387,933T/G—uncertain significance
rs78102597511:46,387,943T/C—uncertain significance
rs56321631411:46,387,951C/T—likely benign
rs36970371211:46,387,952G/A—uncertain significance
rs101079678211:46,387,957C/T—uncertain significance
rs37341986111:46,387,966G/A—uncertain significance
rs37578927411:46,387,984C/T—conflicting classifications of pathogenicity
rs143919293911:46,387,996G/A—uncertain significance
rs194326673611:46,387,998G/C—likely benign
rs76597314911:46,388,005G/C—uncertain significance
rs90199811:46,388,011G/T—benign
rs213645888811:46,388,019C/T—likely benign
rs1182770211:46,388,024G/A—benign
rs75611767311:46,388,026C/T—uncertain significance
rs77778856311:46,388,027G/T—uncertain significance
rs75055069111:46,388,031C/T—likely benign
rs194327239411:46,388,041C/T—uncertain significance
rs194327262311:46,388,042C/T—uncertain significance
rs77044446611:46,388,090A/G—uncertain significance
rs19968224611:46,388,100C/G—benign
rs76049521011:46,388,108C/G—uncertain significance
rs75523144111:46,388,128C/G—uncertain significance
rs37084689511:46,388,143C/T—uncertain significance
rs74531049911:46,388,174A/G—uncertain significance
rs37549546511:46,388,190C/T—likely benign
rs36827455511:46,388,199G/A—benign
rs101575465611:46,388,219C/G—uncertain significance
rs208736011:46,388,220C/T—benign
rs37304261411:46,388,221A/G—uncertain significance
rs75288681011:46,388,227C/G—uncertain significance
rs14291299611:46,388,237C/T—likely benign
rs77923233811:46,388,245C/T—uncertain significance
rs74541127511:46,388,250C/T—likely benign
rs74664251411:46,388,254C/G—uncertain significance
rs36782066111:46,388,255A/G—uncertain significance
rs77648942411:46,388,258C/T—uncertain significance
rs76418627111:46,388,262G/A—likely benign
rs90331886011:46,388,275C/T—uncertain significance
rs57749402011:46,388,276G/A—uncertain significance
rs194332425211:46,388,283G/A—likely benign
rs76979058311:46,388,284C/T—uncertain significance
rs143222588311:46,388,307C/G—likely benign
rs75424588111:46,388,313G/A—uncertain significance
rs121349617911:46,388,322A/G—likely benign
rs77951217211:46,388,324A/T—uncertain significance
rs96243941111:46,388,331C/T—likely benign
rs74645264211:46,388,349C/T—likely benign
rs76843576911:46,388,350G/A—uncertain significance
rs135572541311:46,388,359C/T—uncertain significance
rs142827228211:46,388,362C/G—uncertain significance
rs20103367211:46,388,375G/A—likely benign
rs55865292711:46,388,378G/C—uncertain significance
rs14742167211:46,388,380C/T—uncertain significance
rs76440186211:46,388,410C/G—uncertain significance
rs249643189511:46,388,417C/T—uncertain significance
rs118228267011:46,388,420C/T—uncertain significance
rs119494847311:46,388,431G/A—uncertain significance
rs104232632811:46,388,458C/T—uncertain significance
rs105186067711:46,388,471G/A—uncertain significance
rs75599674611:46,388,485G/C—uncertain significance
rs77672811411:46,388,491C/T—uncertain significance
rs96777993411:46,388,492G/A—uncertain significance
rs74902069111:46,388,506G/A—uncertain significance
rs146799038311:46,388,514G/A—likely benign
rs95930233811:46,388,523C/A—uncertain significance
rs36788612111:46,388,524G/A—benign
rs142583296211:46,388,526C/T—likely benign
rs77422676711:46,388,527C/G—uncertain significance
rs119207470711:46,388,532C/G—likely benign
rs54590785111:46,388,534C/T—uncertain significance

Showing 100 of 347 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.