DLL1

delta like canonical Notch ligand 1

Summary

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]

Known Variants433 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs41269629	6:170,591,768	A/G	—	benign
rs17860720	6:170,591,778	G/A	—	likely benign
rs1033583	6:170,591,923	T/G	downstream gene variant	benign
rs374745563	6:170,591,974	G/A	—	likely benign
rs749369225	6:170,591,975	G/A	—	likely benign
rs80106486	6:170,592,009	A/G	—	benign
rs1546951	6:170,592,020	C/G	—	benign
rs773996573	6:170,592,056	C/T	—	likely benign
rs41269631	6:170,592,057	G/A	—	benign
rs778087366	6:170,592,090	C/T	—	uncertain significance
rs373200536	6:170,592,091	G/A	—	likely benign
rs769642119	6:170,592,092	C/T	—	uncertain significance
rs1412594358	6:170,592,094	C/G	—	uncertain significance
rs775077676	6:170,592,099	C/T	—	uncertain significance
rs1156358956	6:170,592,108	C/A	—	uncertain significance
rs118154169	6:170,592,109	G/A	—	likely benign
rs376347132	6:170,592,111	A/G	—	uncertain significance
rs558852722	6:170,592,117	C/A	—	uncertain significance
rs150208957	6:170,592,118	G/A	—	likely benign
rs760189276	6:170,592,125	G/A	—	uncertain significance
rs1783595866	6:170,592,126	A/G	—	uncertain significance
rs753162814	6:170,592,160	C/G	—	likely benign
rs201177310	6:170,592,161	G/A	—	likely benign
rs75652420	6:170,592,166	C/T	—	likely benign
rs773530345	6:170,592,167	G/A	—	conflicting classifications of pathogenicity
rs933645429	6:170,592,168	G/C	—	uncertain significance
rs1278290381	6:170,592,191	C/G	—	uncertain significance
rs1346035159	6:170,592,209	A/G	—	likely benign
rs902916340	6:170,592,210	G/T	—	likely benign
rs2295205	6:170,592,293	C/G	—	benign
rs201495913	6:170,592,302	C/T	—	likely benign
rs754843439	6:170,592,307	C/T	—	likely benign
rs6929751	6:170,592,308	G/A	—	benign
rs545409782	6:170,592,315	G/A	—	uncertain significance
rs2114957290	6:170,592,317	A/G	—	pathogenic
rs1249992720	6:170,592,322	C/G	—	uncertain significance
rs2483344896	6:170,592,323	T/C	—	uncertain significance
rs777390039	6:170,592,328	G/T	—	uncertain significance
rs776288082	6:170,592,333	C/T	—	likely benign
rs199728521	6:170,592,334	G/A	—	uncertain significance
rs375954659	6:170,592,336	G/T	—	likely benign
rs763570093	6:170,592,341	C/G	—	uncertain significance
rs2483344967	6:170,592,343	T/C	—	uncertain significance
rs751703551	6:170,592,345	C/G	—	uncertain significance
rs111294306	6:170,592,348	C/T	—	likely benign
rs2483345031	6:170,592,359	A/G	—	uncertain significance
rs532671084	6:170,592,361	C/G	—	uncertain significance
rs373176995	6:170,592,366	G/A	—	likely benign
rs1351132593	6:170,592,367	G/T	—	uncertain significance
rs1281454745	6:170,592,369	C/A	—	uncertain significance
rs1159254422	6:170,592,372	G/A	—	likely benign
rs778919888	6:170,592,379	G/A	—	uncertain significance
rs2483345141	6:170,592,382	T/C	—	uncertain significance
rs61757616	6:170,592,386	G/A	—	conflicting classifications of pathogenicity
rs746915006	6:170,592,393	G/A	—	likely benign
rs2483345170	6:170,592,394	T/C	—	uncertain significance
rs780609795	6:170,592,397	G/A	—	conflicting classifications of pathogenicity
rs745583389	6:170,592,398	C/T	—	conflicting classifications of pathogenicity
rs144070852	6:170,592,399	G/C	—	uncertain significance
rs2114957465	6:170,592,403	C/T	—	uncertain significance
rs775884511	6:170,592,407	C/T	—	uncertain significance
rs370263138	6:170,592,408	G/A	—	likely benign
rs769028878	6:170,592,410	C/T	—	conflicting classifications of pathogenicity
rs140596420	6:170,592,411	G/A	—	likely benign
rs767441798	6:170,592,416	C/T	—	uncertain significance
rs570176152	6:170,592,417	G/A	—	likely benign
rs1436745182	6:170,592,424	T/A	—	uncertain significance
rs187849210	6:170,592,437	C/T	—	uncertain significance
rs758149257	6:170,592,438	G/A	—	likely benign
rs552627625	6:170,592,453	C/T	—	likely benign
rs780734657	6:170,592,454	G/A	—	uncertain significance
rs570856641	6:170,592,455	C/T	—	likely benign
rs748926071	6:170,592,463	C/T	—	conflicting classifications of pathogenicity
rs192428019	6:170,592,464	G/A	—	uncertain significance
rs200577178	6:170,592,467	C/T	—	likely benign
rs2483345594	6:170,592,479	T/G	—	uncertain significance
rs780986791	6:170,592,485	C/T	—	uncertain significance
rs201096307	6:170,592,486	G/A	—	likely benign
rs766516902	6:170,592,488	C/T	—	conflicting classifications of pathogenicity
rs371424957	6:170,592,489	G/A	—	likely benign
rs769630735	6:170,592,494	G/T	—	conflicting classifications of pathogenicity
rs763858182	6:170,592,500	C/T	—	uncertain significance
rs142937538	6:170,592,501	G/A	—	likely benign
rs750323375	6:170,592,508	T/C	—	uncertain significance
rs147352089	6:170,592,511	G/A	—	likely benign
rs1583151594	6:170,592,513	C/T	—	likely benign
rs754655881	6:170,592,517	T/G	—	uncertain significance
rs1021386733	6:170,592,533	T/C	—	uncertain significance
rs374942727	6:170,592,534	C/T	—	likely benign
rs975249922	6:170,592,535	T/C	—	uncertain significance
rs778443720	6:170,592,537	C/T	—	likely benign
rs139409566	6:170,592,538	G/A	—	likely benign
rs771135690	6:170,592,545	C/T	—	uncertain significance
rs142517687	6:170,592,546	G/A	—	benign
rs2483346074	6:170,592,572	C/G	—	uncertain significance
rs1783616754	6:170,592,573	A/G	—	likely benign
rs370005717	6:170,592,574	C/T	—	conflicting classifications of pathogenicity
rs2114957805	6:170,592,589	A/C	—	uncertain significance
rs200801825	6:170,592,605	C/A	—	pathogenic
rs199850507	6:170,592,607	G/A	—	conflicting classifications of pathogenicity

Showing 100 of 433 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.