DNAH2

dynein axonemal heavy chain 2

Summary

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

Known Variants405 total

rsidPosition (GRCh37)AllelesClassClinVar
rs75920972917:7,623,044G/T—likely benign
rs75522510917:7,623,114G/C—uncertain significance
rs14579052217:7,623,122C/T—uncertain significance
rs207454468717:7,623,197G/A—uncertain significance
rs135978397517:7,623,200C/T—uncertain significance
rs207454509017:7,623,204C/G—uncertain significance
rs53344307917:7,626,553G/T——
rs1165221917:7,626,567T/G——
rs37388833817:7,630,459G/A—uncertain significance
rs3540636817:7,630,466G/A—benign
rs1186755117:7,630,505C/T—benign
rs6206260917:7,631,694G/Tintron variant—
rs1695693617:7,633,692C/A——
rs76314808717:7,636,408C/A—uncertain significance
rs116674529417:7,636,416G/T—uncertain significance
rs14417228417:7,636,473A/T—likely benign
rs91577717917:7,636,486G/C—uncertain significance
rs11703565717:7,636,497A/G—likely benign
rs20070951717:7,636,511C/T—uncertain significance
rs75333489817:7,636,522C/T—uncertain significance
rs254389529617:7,636,559C/A—uncertain significance
rs207504336317:7,636,597G/T—uncertain significance
rs56324405817:7,636,606C/A—uncertain significance
rs137741036217:7,637,554A/G—uncertain significance
rs76060450917:7,637,561T/A—uncertain significance
rs254390269617:7,637,566C/T—uncertain significance
rs37033726517:7,637,602C/T—uncertain significance
rs374425517:7,637,789C/T—benign
rs120703917217:7,637,809G/A—uncertain significance
rs36917004217:7,637,881T/C—uncertain significance
rs14493413617:7,637,938A/G—likely benign
rs374425417:7,637,982T/A—benign
rs14039278517:7,637,995C/T—likely benign
rs11256255417:7,637,996G/A—benign
rs254390640917:7,638,000T/G—uncertain significance
rs19994558017:7,638,030T/C—likely benign
rs11555909117:7,638,036C/T—likely benign
rs76220967417:7,640,400G/A—uncertain significance
rs100779329417:7,640,425C/T—uncertain significance
rs76592047917:7,640,439C/A—uncertain significance
rs75098338417:7,640,443A/G—uncertain significance
rs53096361017:7,640,513C/A—likely benign
rs20140185617:7,640,532C/T—likely benign
rs102539014317:7,640,534C/T—likely benign
rs133499246017:7,642,336G/A—likely benign
rs15019339017:7,643,057G/A—uncertain significance
rs76347783117:7,643,078C/T—uncertain significance
rs14568657817:7,643,079G/A—uncertain significance
rs20193763217:7,643,094A/G—uncertain significance
rs56376296317:7,643,112G/T—uncertain significance
rs36769160617:7,643,114T/C—uncertain significance
rs14274743117:7,643,152G/A—benign
rs76417194017:7,643,170C/G—uncertain significance
rs139146457217:7,643,188C/A—uncertain significance
rs20108826717:7,643,190C/T—likely benign
rs76916229317:7,643,205G/A—uncertain significance
rs56671853617:7,643,206C/T—likely benign
rs14541546717:7,643,247A/C—uncertain significance
rs20215247517:7,643,729C/A—likely benign
rs75544956617:7,643,773C/G—uncertain significance
rs14241205317:7,643,831T/C—likely benign
rs89375277417:7,644,153A/G—uncertain significance
rs3451126817:7,644,167T/C—likely benign
rs124195059317:7,644,178C/G—uncertain significance
rs7869418517:7,644,253T/C—benign
rs138243633217:7,644,273T/C—uncertain significance
rs254396098717:7,646,258G/T—uncertain significance
rs74977882717:7,646,295G/A—uncertain significance
rs86738690617:7,646,342C/T—uncertain significance
rs14519384617:7,646,429A/G—uncertain significance
rs76831587117:7,646,432G/T—uncertain significance
rs7324854417:7,646,583T/C—benign
rs37479056717:7,646,596C/T—likely benign
rs18109027017:7,646,805A/G—likely benign
rs6206262017:7,659,832G/Adownstream gene variant—
rs15129462317:7,660,416C/T—likely benign
rs76998211517:7,660,429C/T—likely benign
rs37525496017:7,660,485G/A—uncertain significance
rs77233473117:7,661,821C/A—uncertain significance
rs254404843617:7,661,827T/C—uncertain significance
rs103635670117:7,661,857A/G—uncertain significance
rs207592241717:7,662,210T/A—uncertain significance
rs207592301917:7,662,227A/G—uncertain significance
rs116123361917:7,662,246T/C—uncertain significance
rs19994990417:7,662,287C/T—uncertain significance
rs14045990717:7,662,302C/T—uncertain significance
rs77189006417:7,662,314G/A—uncertain significance
rs76057646917:7,662,331G/A—likely benign
rs19962866517:7,662,339G/A—likely benign
rs75160495317:7,662,348G/A—uncertain significance
rs137494241117:7,662,350G/A—uncertain significance
rs78024890617:7,662,380C/T—uncertain significance
rs147676669617:7,662,401A/G—uncertain significance
rs207593040317:7,662,413T/A—uncertain significance
rs36874907517:7,662,414A/G—uncertain significance
rs76518692117:7,662,422T/G—uncertain significance
rs14253208417:7,662,437C/T—conflicting classifications of pathogenicity
rs254405627417:7,662,806A/C—uncertain significance
rs13798375117:7,662,860A/G—uncertain significance
rs146039937417:7,662,908C/T—likely benign

Showing 100 of 405 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.