DNAH8

dynein axonemal heavy chain 8

Summary

The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]

Known Variants1,841 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs111396453	6:38,690,357	G/T	—	benign
rs1699016	6:38,690,359	G/T	—	benign
rs34742890	6:38,690,361	T/G	—	benign
rs34874997	6:38,690,363	T/G	—	benign
rs770813217	6:38,690,577	C/T	—	likely benign
rs774924483	6:38,690,591	G/C	—	uncertain significance
rs565853864	6:38,690,594	G/A	—	likely benign
rs754363459	6:38,690,609	C/T	—	likely benign
rs758575841	6:38,690,618	T/G	—	likely benign
rs777885822	6:38,690,622	G/A	—	uncertain significance
rs780500868	6:38,690,623	G/A	—	likely benign
rs933123302	6:38,690,627	A/C	—	likely benign
rs757017842	6:38,690,628	G/A	—	uncertain significance
rs754105184	6:38,690,632	C/T	—	likely benign
rs1471622411	6:38,690,653	C/A	—	uncertain significance
rs773854540	6:38,690,657	C/T	—	likely benign
rs765662936	6:38,690,669	A/G	—	likely benign
rs767245332	6:38,690,687	G/A	—	likely benign
rs1178576726	6:38,690,691	C/T	—	uncertain significance
rs778551218	6:38,690,697	A/G	—	uncertain significance
rs543402162	6:38,690,699	A/G	—	likely benign
rs777064945	6:38,690,704	A/G	—	uncertain significance
rs1248099376	6:38,690,705	G/A	—	likely benign
rs1182016547	6:38,690,708	C/G	—	likely benign
rs1562544899	6:38,690,711	G/A	—	likely benign
rs776744908	6:38,690,727	T/C	—	uncertain significance
rs767762211	6:38,690,735	C/T	—	likely benign
rs750174047	6:38,690,740	A/G	—	uncertain significance
rs2533983422	6:38,690,741	A/G	—	likely benign
rs778505007	6:38,690,769	C/T	—	uncertain significance
rs770020515	6:38,690,794	G/A	—	uncertain significance
rs1462801040	6:38,690,795	G/A	—	likely benign
rs1357378794	6:38,690,814	C/A	—	uncertain significance
rs1185247828	6:38,690,821	C/T	—	uncertain significance
rs545867507	6:38,690,838	C/T	—	pathogenic
rs1582824738	6:38,690,849	T/G	—	likely benign
rs180723141	6:38,690,855	G/C	—	likely benign
rs757958716	6:38,690,860	C/T	—	uncertain significance
rs185117089	6:38,690,861	G/T	—	likely benign
rs780218121	6:38,690,870	A/G	—	likely benign
rs749695112	6:38,690,886	C/T	—	likely benign
rs768999060	6:38,690,894	G/A	—	likely benign
rs2533985243	6:38,690,895	C/T	—	uncertain significance
rs954540376	6:38,690,896	C/G	—	uncertain significance
rs375770956	6:38,690,903	C/T	—	likely benign
rs2127565118	6:38,690,904	C/G	—	uncertain significance
rs765307487	6:38,690,905	G/A	—	uncertain significance
rs1212995937	6:38,690,911	C/T	—	uncertain significance
rs2533985711	6:38,690,924	C/T	—	likely benign
rs542057474	6:38,690,925	C/T	—	uncertain significance
rs759397600	6:38,690,943	C/T	—	uncertain significance
rs1158694608	6:38,690,951	A/G	—	likely benign
rs780859367	6:38,690,960	A/G	—	likely benign
rs763048415	6:38,690,967	G/A	—	uncertain significance
rs116164504	6:38,690,969	G/C	—	uncertain significance
rs2533986372	6:38,690,980	G/C	—	uncertain significance
rs766979092	6:38,691,145	A/G	—	likely benign
rs753060938	6:38,691,158	C/T	—	uncertain significance
rs371708059	6:38,691,173	A/G	—	uncertain significance
rs376030488	6:38,691,175	A/G	—	uncertain significance
rs374691452	6:38,691,219	T/A	—	uncertain significance
rs2533988786	6:38,691,239	T/C	—	uncertain significance
rs529942973	6:38,691,259	T/G	—	likely benign
rs72856597	6:38,691,352	C/T	—	benign
rs72856598	6:38,691,360	C/T	—	benign
rs9357279	6:38,691,391	C/A	—	benign
rs1698997	6:38,697,386	A/T	—	benign
rs756356607	6:38,697,683	A/G	—	likely benign
rs368460226	6:38,697,703	C/T	—	conflicting classifications of pathogenicity
rs201672902	6:38,697,704	G/A	—	likely benign
rs753974910	6:38,697,710	T/C	—	likely benign
rs748063803	6:38,697,734	G/T	—	uncertain significance
rs56284095	6:38,697,839	A/G	—	benign
rs12212784	6:38,697,844	T/G	—	benign
rs72858210	6:38,698,047	G/A	—	benign
rs9366976	6:38,702,015	T/G	—	benign
rs74904743	6:38,702,169	C/G	—	benign
rs1698996	6:38,702,212	G/A	—	benign
rs559658939	6:38,702,237	C/A	—	likely benign
rs776176679	6:38,702,258	C/T	—	pathogenic
rs200815756	6:38,702,283	G/A	—	uncertain significance
rs750965126	6:38,702,293	G/A	—	uncertain significance
rs761327493	6:38,702,295	T/C	—	uncertain significance
rs149710467	6:38,702,300	T/C	—	likely benign
rs753974456	6:38,702,304	A/G	—	uncertain significance
rs1554195443	6:38,702,307	T/C	—	uncertain significance
rs1249365541	6:38,702,308	A/G	—	uncertain significance
rs1009197625	6:38,702,309	G/A	—	uncertain significance
rs1763929974	6:38,702,310	A/G	—	uncertain significance
rs1763930379	6:38,702,312	A/G	—	uncertain significance
rs548292757	6:38,702,313	A/G	—	uncertain significance
rs199848059	6:38,702,321	C/T	—	uncertain significance
rs370991185	6:38,702,322	C/T	—	uncertain significance
rs202079713	6:38,702,323	G/A	—	likely benign
rs757197800	6:38,702,330	C/T	—	likely benign
rs145773185	6:38,702,357	C/T	—	uncertain significance
rs188018051	6:38,702,358	G/A	—	uncertain significance
rs1007614402	6:38,702,361	G/C	—	uncertain significance
rs79455046	6:38,702,363	C/T	—	benign
rs142863013	6:38,702,364	G/A	—	conflicting classifications of pathogenicity

Showing 100 of 1,841 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.