DOK3
docking protein 3
Summary
Predicted to be involved in Ras protein signal transduction and cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in ficolin-1-rich granule membrane and plasma membrane. Predicted to be active in cytoplasm. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants55 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs528437635 | 5:176,930,117 | G/A | — | uncertain significance |
| rs201537959 | 5:176,930,140 | T/C | — | uncertain significance |
| rs2279398 | 5:176,930,769 | C/T | downstream gene variant | — |
| rs1480485056 | 5:176,930,991 | C/G | — | uncertain significance |
| rs1759661591 | 5:176,930,993 | G/C | — | uncertain significance |
| rs754987743 | 5:176,931,000 | G/C | — | uncertain significance |
| rs754746787 | 5:176,931,024 | C/T | — | uncertain significance |
| rs373998463 | 5:176,931,027 | C/T | — | uncertain significance |
| rs1211795086 | 5:176,931,052 | T/C | — | uncertain significance |
| rs756794198 | 5:176,931,139 | C/T | — | uncertain significance |
| rs61749655 | 5:176,931,140 | G/A | synonymous variant | — |
| rs376367966 | 5:176,931,147 | G/A | — | uncertain significance |
| rs1283695200 | 5:176,931,172 | C/T | — | likely benign |
| rs2531992094 | 5:176,931,219 | T/G | — | uncertain significance |
| rs770447953 | 5:176,931,249 | G/A | — | uncertain significance |
| rs541916027 | 5:176,931,304 | G/T | — | uncertain significance |
| rs768097446 | 5:176,931,315 | C/T | — | uncertain significance |
| rs546444181 | 5:176,931,340 | C/T | — | uncertain significance |
| rs144901160 | 5:176,931,345 | G/A | — | uncertain significance |
| rs767157132 | 5:176,931,351 | T/G | — | uncertain significance |
| rs763369194 | 5:176,931,352 | C/A | — | uncertain significance |
| rs138777903 | 5:176,931,354 | T/C | — | likely benign |
| rs367712454 | 5:176,931,378 | G/A | — | uncertain significance |
| rs371251523 | 5:176,931,423 | G/A | — | uncertain significance |
| rs755563039 | 5:176,931,537 | C/T | — | uncertain significance |
| rs377570203 | 5:176,931,538 | G/A | — | uncertain significance |
| rs367771899 | 5:176,931,651 | G/A | — | uncertain significance |
| rs145507014 | 5:176,931,658 | C/T | — | uncertain significance |
| rs748085171 | 5:176,931,773 | G/A | — | uncertain significance |
| rs141898162 | 5:176,931,787 | T/C | — | uncertain significance |
| rs752693479 | 5:176,931,872 | G/A | — | uncertain significance |
| rs201667045 | 5:176,931,878 | C/T | — | uncertain significance |
| rs267600571 | 5:176,931,902 | C/T | — | uncertain significance |
| rs199714101 | 5:176,932,096 | A/G | — | uncertain significance |
| rs533549383 | 5:176,932,987 | T/C | — | — |
| rs368466434 | 5:176,935,239 | G/A | — | uncertain significance |
| rs766977751 | 5:176,935,279 | G/A | — | uncertain significance |
| rs1450419965 | 5:176,935,305 | C/T | — | uncertain significance |
| rs375564754 | 5:176,935,309 | C/T | — | uncertain significance |
| rs1760495035 | 5:176,935,339 | C/A | — | uncertain significance |
| rs142573859 | 5:176,935,341 | C/A | — | uncertain significance |
| rs1048324258 | 5:176,935,425 | C/T | — | uncertain significance |
| rs369375986 | 5:176,935,462 | C/T | — | uncertain significance |
| rs1375659637 | 5:176,935,492 | C/T | — | uncertain significance |
| rs768720226 | 5:176,935,509 | G/A | — | uncertain significance |
| rs2532053752 | 5:176,936,508 | T/C | — | uncertain significance |
| rs193120614 | 5:176,936,564 | G/A | — | uncertain significance |
| rs372299396 | 5:176,936,610 | C/T | — | uncertain significance |
| rs549783080 | 5:176,936,639 | G/A | — | uncertain significance |
| rs748595732 | 5:176,936,643 | C/A | — | uncertain significance |
| rs375009995 | 5:176,936,823 | C/G | — | uncertain significance |
| rs149834473 | 5:176,936,831 | C/T | — | uncertain significance |
| rs1381539865 | 5:176,936,843 | C/T | — | uncertain significance |
| rs764296074 | 5:176,936,846 | C/G | — | uncertain significance |
| rs558150906 | 5:176,936,847 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.