DRG1
developmentally regulated GTP binding protein 1
Summary
Enables several functions, including GTPase activity; identical protein binding activity; and potassium ion binding activity. Involved in positive regulation of microtubule polymerization and regulation of mitotic spindle assembly. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants13 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2049955711 | 22:31,796,605 | G/T | — | uncertain significance |
| rs1391978939 | 22:31,796,681 | C/T | — | likely pathogenic |
| rs143000666 | 22:31,796,690 | A/G | — | uncertain significance |
| rs2518503242 | 22:31,796,723 | G/T | — | likely pathogenic |
| rs2518504624 | 22:31,799,045 | G/A | — | uncertain significance |
| rs695304 | 22:31,801,666 | T/C | — | — |
| rs35955747 | 22:31,813,058 | A/G | — | — |
| rs1459583728 | 22:31,816,247 | C/T | — | likely pathogenic |
| rs150581672 | 22:31,819,281 | C/A | — | uncertain significance |
| rs2517546324 | 22:31,819,351 | G/A | — | uncertain significance |
| rs2517548621 | 22:31,822,674 | A/T | — | likely pathogenic |
| rs201137214 | 22:31,823,107 | A/G | — | uncertain significance |
| rs2517549007 | 22:31,823,164 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.