ELAC1
elaC ribonuclease Z 1
Summary
Enables tRNA-specific ribonuclease activity. Involved in rescue of stalled ribosome and tRNA 3'-end processing. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants21 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs201522971 | 18:48,500,829 | C/T | — | uncertain significance |
| rs370108749 | 18:48,500,854 | G/A | — | uncertain significance |
| rs2511339869 | 18:48,510,526 | G/A | — | uncertain significance |
| rs144276133 | 18:48,510,555 | G/C | — | uncertain significance |
| rs2511340066 | 18:48,510,651 | G/C | — | uncertain significance |
| rs142132015 | 18:48,510,696 | T/C | missense variant | — |
| rs144462801 | 18:48,510,781 | T/C | — | uncertain significance |
| rs200639182 | 18:48,510,798 | T/A | — | uncertain significance |
| rs139447573 | 18:48,510,843 | C/T | — | uncertain significance |
| rs749079789 | 18:48,510,846 | C/G | — | uncertain significance |
| rs2144324820 | 18:48,510,892 | A/C | — | uncertain significance |
| rs373421001 | 18:48,510,895 | G/A | — | uncertain significance |
| rs751258412 | 18:48,510,900 | G/C | — | uncertain significance |
| rs201796024 | 18:48,513,080 | A/T | — | uncertain significance |
| rs1908117020 | 18:48,513,088 | C/T | — | uncertain significance |
| rs2511342084 | 18:48,513,169 | C/A | — | uncertain significance |
| rs752476108 | 18:48,513,186 | G/A | — | uncertain significance |
| rs1249958873 | 18:48,513,208 | A/T | — | uncertain significance |
| rs755540725 | 18:48,513,217 | A/C | — | uncertain significance |
| rs777442836 | 18:48,513,240 | A/T | — | uncertain significance |
| rs776088986 | 18:48,513,276 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.