EXOSC5
exosome component 5
Summary
Predicted to enable RNA binding activity. Involved in DNA deamination; RNA processing; and mRNA catabolic process. Acts upstream of or within defense response to virus. Located in cytosol; euchromatin; and nuclear lumen. Part of exosome (RNase complex). [provided by Alliance of Genome Resources, Jul 2025]
Known Variants38 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs8103531 | 19:41,891,974 | C/T | downstream gene variant | — |
| rs3826713 | 19:41,892,269 | C/G | — | — |
| rs2513437037 | 19:41,892,543 | T/C | — | uncertain significance |
| rs751654580 | 19:41,892,581 | C/T | — | uncertain significance |
| rs147964002 | 19:41,892,582 | G/A | — | uncertain significance |
| rs1309806787 | 19:41,892,583 | G/C | — | uncertain significance |
| rs758033402 | 19:41,892,600 | C/T | — | uncertain significance |
| rs2123217925 | 19:41,892,629 | A/T | — | pathogenic |
| rs370678317 | 19:41,893,479 | C/G | — | likely benign |
| rs201468947 | 19:41,893,501 | C/T | — | likely benign |
| rs199691911 | 19:41,895,674 | T/C | — | uncertain significance |
| rs377108451 | 19:41,895,699 | C/T | — | uncertain significance |
| rs1471491159 | 19:41,895,711 | C/A | — | uncertain significance |
| rs138658713 | 19:41,895,722 | G/A | — | uncertain significance |
| rs202054918 | 19:41,895,732 | C/A | — | uncertain significance |
| rs367988911 | 19:41,895,752 | A/G | — | uncertain significance |
| rs376614222 | 19:41,895,786 | C/T | — | uncertain significance |
| rs8105833 | 19:41,896,145 | G/C | — | — |
| rs878083 | 19:41,897,688 | G/A | intron variant | — |
| rs201990827 | 19:41,897,751 | C/G | — | uncertain significance |
| rs762509910 | 19:41,897,777 | A/G | — | uncertain significance |
| rs542429051 | 19:41,897,789 | G/A | — | pathogenic |
| rs752487650 | 19:41,897,792 | C/T | — | uncertain significance |
| rs1293880910 | 19:41,897,819 | G/A | — | uncertain significance |
| rs780441782 | 19:41,897,823 | C/T | — | uncertain significance |
| rs777418116 | 19:41,897,828 | G/T | — | pathogenic |
| rs753050670 | 19:41,898,805 | C/T | — | uncertain significance |
| rs143874550 | 19:41,898,809 | T/C | — | likely benign |
| rs183362480 | 19:41,898,847 | C/T | — | uncertain significance |
| rs557342298 | 19:41,898,867 | G/A | — | uncertain significance |
| rs11667908 | 19:41,900,124 | G/A | upstream gene variant | — |
| rs75842718 | 19:41,901,288 | C/T | regulatory region variant | — |
| rs183705571 | 19:41,903,115 | C/G | — | uncertain significance |
| rs757053812 | 19:41,903,184 | G/A | — | uncertain significance |
| rs547685483 | 19:41,903,210 | G/C | — | uncertain significance |
| rs770305782 | 19:41,903,217 | T/C | — | uncertain significance |
| rs10853751 | 19:41,903,220 | G/A | — | benign |
| rs2513442812 | 19:41,903,223 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.