FLII

FLII actin remodeling protein

Summary

This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Known Variants120 total

rsidPosition (GRCh37)AllelesClassClinVar
rs204798383717:18,148,469A/G—likely benign
rs20079910017:18,148,476G/A—likely benign
rs156770149917:18,148,490A/G—uncertain significance
rs56322594117:18,148,544G/A—likely pathogenic
rs20191225117:18,148,549C/T—likely benign
rs13840609417:18,148,550G/A—uncertain significance
rs13908312117:18,148,884T/A—benign
rs19952429717:18,148,962C/G—uncertain significance
rs7750654617:18,148,965G/A—likely benign
rs37706403617:18,149,059G/A—pathogenic
rs14401306117:18,149,093G/A—benign
rs204802279517:18,149,113C/A—uncertain significance
rs159789496117:18,149,152C/T—uncertain significance
rs1154088617:18,149,308G/A—likely benign
rs75815894717:18,149,325G/A—uncertain significance
rs96524324117:18,149,365C/G—uncertain significance
rs75884482517:18,149,496C/G—uncertain significance
rs74733792117:18,149,507A/C—uncertain significance
rs74581304017:18,149,649C/T—uncertain significance
rs37549812717:18,149,650G/A—uncertain significance
rs77529869817:18,149,658T/A—uncertain significance
rs76469865717:18,149,677C/T—likely benign
rs75630885617:18,149,687C/T—likely benign
rs14830587917:18,149,710T/C—uncertain significance
rs159789764517:18,149,755G/C—uncertain significance
rs76801531617:18,149,770G/A—uncertain significance
rs55924810617:18,150,032G/A—uncertain significance
rs20045548717:18,150,086T/G—conflicting classifications of pathogenicity
rs254550010517:18,150,093C/T—uncertain significance
rs14178054917:18,150,148G/A—benign
rs13859548917:18,150,224T/C—likely benign
rs95182640617:18,150,241G/A—likely benign
rs7782172217:18,150,288G/A—uncertain significance
rs254550166317:18,150,290G/T—uncertain significance
rs123843422717:18,150,474T/C—likely benign
rs77497699217:18,150,496A/G—uncertain significance
rs37427844717:18,150,546G/C—uncertain significance
rs76117053617:18,150,550T/G—uncertain significance
rs75041895817:18,150,566G/A—uncertain significance
rs119376803217:18,150,572C/G—uncertain significance
rs254550484917:18,150,606C/G—uncertain significance
rs101459355617:18,150,619G/T—uncertain significance
rs53598489117:18,151,009C/T—uncertain significance
rs204812798617:18,151,060C/T—uncertain significance
rs127789090217:18,151,082G/A—likely benign
rs57563232117:18,151,105A/G—uncertain significance
rs136634471517:18,151,111C/T—uncertain significance
rs20067360517:18,151,172G/C—likely benign
rs125205274217:18,151,290C/T—uncertain significance
rs90901879917:18,151,312C/A—uncertain significance
rs14894384517:18,151,886G/A—uncertain significance
rs37405434717:18,152,003C/T—uncertain significance
rs139145509117:18,152,034G/C—uncertain significance
rs254551427817:18,152,135A/T—uncertain significance
rs77963444417:18,152,147G/T—uncertain significance
rs54775639617:18,152,154G/C—uncertain significance
rs76281573917:18,152,178G/A—uncertain significance
rs138409109817:18,152,197C/A—uncertain significance
rs78076353217:18,152,444G/C—uncertain significance
rs77416299517:18,152,473A/G—likely benign
rs19959581317:18,152,475G/A—uncertain significance
rs77178901917:18,152,485G/T—likely benign
rs54367315817:18,152,649T/C—uncertain significance
rs13805939317:18,152,667G/A—benign
rs37072990717:18,154,142G/A—benign
rs75378327517:18,154,167G/A—likely benign
rs14925897417:18,154,175C/T—uncertain significance
rs14446356117:18,154,176G/A—likely benign
rs254552352217:18,154,213A/C—uncertain significance
rs77340869517:18,154,232C/T—uncertain significance
rs6173842017:18,154,236G/A—benign
rs75362870817:18,154,276C/T—uncertain significance
rs138052907217:18,154,330G/T—uncertain significance
rs207124217:18,154,510T/Cintron variant—
rs76600577817:18,154,609G/T—uncertain significance
rs74629308317:18,154,647C/T—uncertain significance
rs137001591217:18,154,667A/G—uncertain significance
rs37550850717:18,154,700G/A—uncertain significance
rs11643150617:18,154,711G/A—benign
rs204826375417:18,154,717G/C—uncertain significance
rs14482995717:18,154,723G/A—likely benign
rs37048274317:18,154,771G/T—likely benign
rs254552688217:18,154,778G/A—uncertain significance
rs204827393017:18,155,017G/A—pathogenic
rs254552873017:18,155,044C/T—uncertain significance
rs77538758517:18,155,091C/T—uncertain significance
rs93259674117:18,155,093C/A—uncertain significance
rs74794748517:18,155,100C/T—uncertain significance
rs254552931217:18,155,130G/C—uncertain significance
rs15000795617:18,155,331C/T—benign
rs76221758817:18,155,382C/T—uncertain significance
rs11773926117:18,155,401G/A—benign
rs137923845517:18,155,406G/T—uncertain significance
rs123081982617:18,155,458G/C—likely benign
rs6174178417:18,155,793T/A—likely benign
rs260514017:18,156,375A/Gintron variant—
rs118719969817:18,156,693C/T—uncertain significance
rs15031765517:18,156,759T/C—uncertain significance
rs36915583617:18,156,967C/T—uncertain significance
rs77379542217:18,156,968G/A—uncertain significance

Showing 100 of 120 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.