FLYWCH1

FLYWCH-type zinc finger 1

Summary

Enables transcription coactivator binding activity and transcription corepressor activity. Involved in DNA damage response and negative regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and pericentric heterochromatin. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants103 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs533022433	16:2,965,779	C/G	—	—
rs756132703	16:2,979,732	G/T	—	uncertain significance
rs757667264	16:2,979,735	G/A	—	uncertain significance
rs373220766	16:2,979,763	C/T	—	uncertain significance
rs748843365	16:2,979,767	C/A	—	uncertain significance
rs373096823	16:2,979,794	C/G	—	likely benign
rs1367347478	16:2,979,798	G/A	—	likely benign
rs112444415	16:2,979,879	G/A	—	uncertain significance
rs771888603	16:2,979,888	C/A	—	uncertain significance
rs376062192	16:2,979,906	G/A	—	uncertain significance
rs370723003	16:2,979,998	C/A	—	uncertain significance
rs146665306	16:2,980,006	A/G	—	likely benign
rs761017441	16:2,980,431	T/C	—	uncertain significance
rs753873848	16:2,980,437	A/G	—	uncertain significance
rs989578520	16:2,980,456	G/A	—	uncertain significance
rs1272263402	16:2,980,487	G/C	—	uncertain significance
rs777892980	16:2,980,500	G/A	—	uncertain significance
rs1047390739	16:2,980,520	G/C	—	uncertain significance
rs201482326	16:2,980,527	C/T	—	uncertain significance
rs373564797	16:2,980,534	A/G	—	uncertain significance
rs376432894	16:2,980,558	G/A	—	uncertain significance
rs374701808	16:2,980,559	G/A	—	likely benign
rs376592191	16:2,980,570	G/A	—	uncertain significance
rs371073892	16:2,980,579	G/A	—	uncertain significance
rs780307376	16:2,980,608	G/A	—	uncertain significance
rs534891725	16:2,980,635	C/T	—	uncertain significance
rs2505820619	16:2,980,680	T/A	—	uncertain significance
rs770022454	16:2,980,710	G/C	—	uncertain significance
rs201356969	16:2,980,747	C/T	—	likely benign
rs188049330	16:2,980,802	G/A	—	benign
rs982888396	16:2,980,804	C/T	—	uncertain significance
rs779560750	16:2,980,812	G/A	—	uncertain significance
rs1353513126	16:2,980,867	C/T	—	uncertain significance
rs1376229106	16:2,980,875	G/A	—	uncertain significance
rs373503381	16:2,983,140	G/A	—	likely benign
rs1451315993	16:2,983,172	G/C	—	uncertain significance
rs777839097	16:2,983,218	C/T	—	uncertain significance
rs1294881361	16:2,983,226	G/C	—	uncertain significance
rs199520906	16:2,983,244	T/G	—	uncertain significance
rs1166569424	16:2,983,283	A/G	—	uncertain significance
rs1054704223	16:2,983,287	C/A	—	uncertain significance
rs750659441	16:2,983,298	C/T	—	uncertain significance
rs768884431	16:2,983,314	G/A	—	uncertain significance
rs370537064	16:2,983,317	G/C	—	uncertain significance
rs199955271	16:2,983,339	G/A	—	uncertain significance
rs776637150	16:2,983,346	C/G	—	uncertain significance
rs758445226	16:2,983,356	G/A	—	uncertain significance
rs199890568	16:2,983,375	C/T	—	benign
rs551653171	16:2,983,376	G/A	—	likely benign
rs372295012	16:2,983,383	C/T	—	uncertain significance
rs201614423	16:2,983,403	G/A	—	uncertain significance
rs758011834	16:2,983,409	G/C	—	uncertain significance
rs369927951	16:2,983,434	G/A	—	likely benign
rs757899219	16:2,983,439	G/A	—	uncertain significance
rs201142918	16:2,983,445	A/T	—	uncertain significance
rs370131723	16:2,983,458	G/A	—	likely benign
rs375862744	16:2,983,467	C/T	—	uncertain significance
rs372562253	16:2,983,482	T/C	—	uncertain significance
rs200267787	16:2,983,494	G/A	—	likely benign
rs202152304	16:2,983,506	G/C	—	uncertain significance
rs370126317	16:2,983,533	C/T	—	uncertain significance
rs373457523	16:2,983,550	C/A	—	uncertain significance
rs375241000	16:2,983,561	C/G	—	uncertain significance
rs990991540	16:2,983,562	C/G	—	uncertain significance
rs2505871383	16:2,983,759	T/C	—	uncertain significance
rs1443327967	16:2,983,769	G/C	—	uncertain significance
rs781769133	16:2,983,808	G/A	—	likely benign
rs1313670616	16:2,983,824	C/T	—	uncertain significance
rs768400408	16:2,983,825	G/A	—	uncertain significance
rs1184112985	16:2,983,836	C/T	—	uncertain significance
rs763060207	16:2,983,839	A/G	—	uncertain significance
rs375529753	16:2,983,848	C/T	—	uncertain significance
rs370778623	16:2,983,870	G/A	—	uncertain significance
rs773182057	16:2,983,881	A/C	—	uncertain significance
rs539929256	16:2,983,895	T/G	—	likely benign
rs561208649	16:2,983,941	C/G	—	uncertain significance
rs775834806	16:2,983,950	C/T	—	uncertain significance
rs746049171	16:2,983,969	G/A	—	uncertain significance
rs372102621	16:2,987,124	G/A	—	uncertain significance
rs748205788	16:2,987,143	C/T	—	uncertain significance
rs887044950	16:2,987,152	G/A	—	uncertain significance
rs748059598	16:2,987,191	G/A	—	uncertain significance
rs375339876	16:2,987,205	G/T	—	uncertain significance
rs535856688	16:2,987,229	C/T	—	uncertain significance
rs1027261844	16:2,987,244	A/G	—	uncertain significance
rs777800252	16:2,987,280	C/T	—	uncertain significance
rs748711943	16:2,987,314	C/T	—	uncertain significance
rs1369031565	16:2,987,323	G/A	—	uncertain significance
rs61747748	16:2,987,325	G/A	—	benign
rs2505926551	16:2,987,382	C/G	—	uncertain significance
rs571469602	16:2,988,207	C/G	—	uncertain significance
rs771995061	16:2,988,280	G/C	—	uncertain significance
rs750748295	16:2,988,301	C/T	—	uncertain significance
rs747123635	16:2,988,332	G/A	—	uncertain significance
rs201029011	16:2,988,334	G/A	—	uncertain significance
rs957676175	16:2,988,360	G/C	—	uncertain significance
rs2505942239	16:2,988,406	G/A	—	uncertain significance
rs370461102	16:2,988,418	C/T	—	uncertain significance
rs767882824	16:2,988,437	C/T	—	uncertain significance
rs202209107	16:2,988,450	G/C	—	uncertain significance

Showing 100 of 103 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.