FPR2
formyl peptide receptor 2
Summary
Enables amyloid-beta binding activity; scavenger receptor binding activity; and signaling receptor activity. Involved in several processes, including cellular response to amyloid-beta; positive regulation of ERK1 and ERK2 cascade; and regulation of defense response. Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants25 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11666254 | 19:52,263,162 | A/C | — | — |
| rs184883925 | 19:52,265,760 | G/A | upstream gene variant | — |
| rs2513930828 | 19:52,265,885 | C/T | — | uncertain significance |
| rs778561198 | 19:52,271,988 | G/A | — | likely benign |
| rs749741937 | 19:52,272,029 | G/A | — | uncertain significance |
| rs142611552 | 19:52,272,080 | C/T | — | uncertain significance |
| rs2083882266 | 19:52,272,086 | G/A | — | uncertain significance |
| rs74602258 | 19:52,272,131 | T/C | — | likely benign |
| rs144552448 | 19:52,272,135 | C/T | — | uncertain significance |
| rs765433312 | 19:52,272,165 | T/C | — | uncertain significance |
| rs2513935037 | 19:52,272,194 | T/C | — | uncertain significance |
| rs886383123 | 19:52,272,294 | T/G | — | uncertain significance |
| rs529128829 | 19:52,272,353 | G/A | — | uncertain significance |
| rs202141015 | 19:52,272,434 | T/C | — | uncertain significance |
| rs141356657 | 19:52,272,549 | C/T | — | uncertain significance |
| rs776426296 | 19:52,272,645 | C/T | — | uncertain significance |
| rs1361960096 | 19:52,272,647 | G/A | — | uncertain significance |
| rs199737333 | 19:52,272,664 | C/G | — | uncertain significance |
| rs554489638 | 19:52,272,707 | G/A | — | uncertain significance |
| rs200871443 | 19:52,272,727 | G/C | — | uncertain significance |
| rs959115098 | 19:52,272,770 | A/G | — | uncertain significance |
| rs200897681 | 19:52,272,799 | C/G | — | uncertain significance |
| rs1667840771 | 19:52,272,815 | T/C | — | uncertain significance |
| rs373596683 | 19:52,272,818 | G/C | — | uncertain significance |
| rs1284602219 | 19:52,272,844 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.