FRZB
frizzled related protein
Summary
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. [provided by RefSeq, Apr 2010]
Known Variants35 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs16823799 | 2:183,698,691 | G/A | 3 prime UTR variant | — |
| rs13009 | 2:183,699,364 | C/T | 3 prime UTR variant | — |
| rs7775 | 2:183,699,584 | G/A | missense variant | risk factor |
| rs41270213 | 2:183,699,648 | G/A | — | benign |
| rs146454508 | 2:183,699,673 | C/T | — | uncertain significance |
| rs112094045 | 2:183,699,682 | A/G | — | likely benign |
| rs111740973 | 2:183,702,670 | G/T | — | likely benign |
| rs373539605 | 2:183,702,690 | C/T | — | uncertain significance |
| rs775764533 | 2:183,702,722 | C/G | — | uncertain significance |
| rs141551747 | 2:183,703,143 | C/T | — | uncertain significance |
| rs185490352 | 2:183,703,144 | G/A | — | uncertain significance |
| rs138147194 | 2:183,703,147 | C/T | — | uncertain significance |
| rs139802041 | 2:183,703,181 | A/G | — | likely benign |
| rs751192699 | 2:183,703,219 | T/C | — | uncertain significance |
| rs367887067 | 2:183,703,227 | T/C | — | uncertain significance |
| rs112797950 | 2:183,703,239 | C/T | missense variant | — |
| rs758867782 | 2:183,703,247 | G/T | — | uncertain significance |
| rs288326 | 2:183,703,336 | G/A | missense variant | risk factor |
| rs752029877 | 2:183,703,341 | A/G | — | uncertain significance |
| rs75466155 | 2:183,706,804 | T/A | — | — |
| rs145951169 | 2:183,707,220 | T/C | — | uncertain significance |
| rs767819242 | 2:183,707,234 | C/A | — | uncertain significance |
| rs752928002 | 2:183,707,242 | T/C | — | uncertain significance |
| rs757699577 | 2:183,715,135 | A/T | — | — |
| rs7602601 | 2:183,722,966 | T/C | intron variant | — |
| rs144510376 | 2:183,730,831 | G/T | — | likely benign |
| rs151046356 | 2:183,730,848 | C/T | — | uncertain significance |
| rs1410683757 | 2:183,730,914 | G/A | — | uncertain significance |
| rs899005454 | 2:183,730,916 | A/T | — | uncertain significance |
| rs139461108 | 2:183,730,988 | A/G | — | uncertain significance |
| rs767399953 | 2:183,731,037 | G/A | — | uncertain significance |
| rs541564082 | 2:183,731,047 | G/A | — | likely benign |
| rs759725355 | 2:183,731,141 | G/A | — | uncertain significance |
| rs764919902 | 2:183,731,166 | G/C | — | uncertain significance |
| rs749714954 | 2:183,731,205 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.