FSTL4
follistatin like 4
Summary
Predicted to enable brain-derived neurotrophic factor binding activity and calcium ion binding activity. Predicted to be involved in cell differentiation and regulation of BMP signaling pathway. Predicted to act upstream of or within negative regulation of brain-derived neurotrophic factor receptor signaling pathway; negative regulation of collateral sprouting; and negative regulation of dendritic spine development. Predicted to be located in secretory granule. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants70 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs558686290 | 5:132,534,822 | C/T | — | likely benign |
| rs150466282 | 5:132,534,846 | G/A | — | uncertain significance |
| rs143025521 | 5:132,534,887 | C/A | — | uncertain significance |
| rs372625937 | 5:132,534,939 | T/C | — | uncertain significance |
| rs779770295 | 5:132,534,947 | C/T | — | uncertain significance |
| rs748430487 | 5:132,534,972 | C/T | — | likely benign |
| rs1452356941 | 5:132,535,013 | G/A | — | uncertain significance |
| rs1487669312 | 5:132,535,056 | C/T | — | likely benign |
| rs761904423 | 5:132,535,061 | T/G | — | uncertain significance |
| rs1750248286 | 5:132,535,118 | C/T | — | uncertain significance |
| rs551036078 | 5:132,535,121 | G/A | — | uncertain significance |
| rs141195594 | 5:132,535,129 | T/C | — | likely benign |
| rs2533191509 | 5:132,535,208 | C/T | — | uncertain significance |
| rs149501035 | 5:132,535,220 | C/T | — | uncertain significance |
| rs61740558 | 5:132,535,225 | G/A | — | benign |
| rs748954143 | 5:132,535,296 | C/T | — | likely benign |
| rs185850111 | 5:132,535,356 | C/T | — | uncertain significance |
| rs190274064 | 5:132,535,362 | G/C | — | uncertain significance |
| rs144664634 | 5:132,535,382 | T/C | — | uncertain significance |
| rs147873655 | 5:132,535,433 | G/T | — | uncertain significance |
| rs762679724 | 5:132,535,464 | C/G | — | uncertain significance |
| rs61741673 | 5:132,537,644 | G/A | — | likely benign |
| rs1750336746 | 5:132,537,679 | G/A | — | uncertain significance |
| rs763576209 | 5:132,537,691 | C/T | — | uncertain significance |
| rs151054673 | 5:132,537,692 | G/A | — | uncertain significance |
| rs144623724 | 5:132,552,994 | C/T | — | uncertain significance |
| rs748835993 | 5:132,552,997 | T/G | — | uncertain significance |
| rs370187282 | 5:132,556,475 | G/A | — | uncertain significance |
| rs201737601 | 5:132,556,520 | C/T | — | uncertain significance |
| rs140221506 | 5:132,556,523 | C/T | — | benign |
| rs199589963 | 5:132,556,524 | G/A | — | likely benign |
| rs73273886 | 5:132,560,834 | C/T | — | benign |
| rs1052929257 | 5:132,560,950 | T/C | — | uncertain significance |
| rs753800956 | 5:132,560,963 | T/A | — | uncertain significance |
| rs376207233 | 5:132,561,392 | C/T | — | likely benign |
| rs2533274061 | 5:132,561,415 | C/A | — | uncertain significance |
| rs536261992 | 5:132,564,773 | C/T | — | — |
| rs61741670 | 5:132,569,146 | G/A | — | benign |
| rs758989810 | 5:132,569,178 | T/C | — | uncertain significance |
| rs569903433 | 5:132,572,365 | C/T | — | — |
| rs1173282927 | 5:132,585,127 | T/A | — | uncertain significance |
| rs2533329909 | 5:132,585,172 | T/A | — | uncertain significance |
| rs151107205 | 5:132,585,176 | C/T | — | uncertain significance |
| rs151288928 | 5:132,585,182 | C/A | — | uncertain significance |
| rs200532258 | 5:132,585,185 | C/T | — | uncertain significance |
| rs138802581 | 5:132,585,242 | C/T | — | uncertain significance |
| rs115281368 | 5:132,626,032 | C/T | regulatory region variant | — |
| rs17166496 | 5:132,628,884 | G/C | intron variant | — |
| rs746318020 | 5:132,648,367 | G/A | — | uncertain significance |
| rs199581768 | 5:132,648,415 | C/G | — | uncertain significance |
| rs1421369921 | 5:132,648,466 | C/G | — | uncertain significance |
| rs150612886 | 5:132,652,163 | G/A | — | likely benign |
| rs746146996 | 5:132,652,342 | C/T | — | uncertain significance |
| rs2479593195 | 5:132,736,481 | G/A | — | uncertain significance |
| rs778985526 | 5:132,736,496 | G/A | — | uncertain significance |
| rs1341669590 | 5:132,736,589 | C/T | — | uncertain significance |
| rs770671021 | 5:132,736,601 | T/A | — | uncertain significance |
| rs368837848 | 5:132,736,615 | C/T | — | uncertain significance |
| rs140375656 | 5:132,736,616 | G/A | — | uncertain significance |
| rs754029268 | 5:132,736,624 | C/T | — | uncertain significance |
| rs751517490 | 5:132,736,657 | A/G | — | uncertain significance |
| rs1299159657 | 5:132,902,907 | G/A | — | likely benign |
| rs143252980 | 5:132,939,616 | G/A | — | likely benign |
| rs763456563 | 5:132,939,635 | C/T | — | uncertain significance |
| rs6596140 | 5:133,021,851 | C/T | intergenic variant | — |
| rs62373497 | 5:133,035,923 | C/T | — | — |
| rs547978690 | 5:133,069,569 | G/A | — | — |
| rs568924312 | 5:133,140,492 | G/A | — | — |
| rs192448988 | 5:133,144,860 | C/T | intergenic variant | — |
| rs2457174 | 5:133,179,080 | C/T | intergenic variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.