GALP

galanin like peptide

Summary

This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors.[provided by RefSeq, Nov 2014]

Known Variants12 total

rsidPosition (GRCh37)AllelesClassClinVar
rs36820073419:56,688,493G/Auncertain significance
rs251416833419:56,688,502G/Cuncertain significance
rs251416837519:56,688,527G/Tuncertain significance
rs74948723119:56,688,556G/Auncertain significance
rs14730575719:56,688,557C/Tlikely benign
rs19951409819:56,688,563G/Alikely benign
rs11126512519:56,688,781G/Cintron variant
rs14985363819:56,691,959G/Auncertain significance
rs76789883319:56,691,982G/Tuncertain significance
rs37144301919:56,694,576T/Cuncertain significance
rs53841272819:56,696,184G/A
rs77098980919:56,696,618G/Tuncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.