GBP4
guanylate binding protein 4
Summary
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
Known Variants34 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs571510254 | 1:89,648,307 | G/A | — | — |
| rs35117143 | 1:89,651,039 | G/A | — | likely benign |
| rs529438124 | 1:89,652,129 | C/G | — | uncertain significance |
| rs992168255 | 1:89,652,727 | A/G | — | uncertain significance |
| rs1352056374 | 1:89,654,364 | C/G | — | uncertain significance |
| rs745623781 | 1:89,654,377 | G/A | — | uncertain significance |
| rs150651435 | 1:89,654,427 | T/C | — | likely benign |
| rs771932371 | 1:89,654,428 | G/A | — | uncertain significance |
| rs757189488 | 1:89,654,470 | A/G | — | uncertain significance |
| rs374581949 | 1:89,655,734 | T/C | — | uncertain significance |
| rs778109948 | 1:89,655,810 | C/T | — | uncertain significance |
| rs751784119 | 1:89,655,866 | T/G | — | uncertain significance |
| rs558982077 | 1:89,655,880 | G/A | — | likely benign |
| rs763766416 | 1:89,655,902 | G/A | — | uncertain significance |
| rs145816730 | 1:89,655,911 | A/G | — | uncertain significance |
| rs1399797354 | 1:89,655,914 | T/C | — | uncertain significance |
| rs2523780992 | 1:89,655,944 | C/G | — | uncertain significance |
| rs61738489 | 1:89,656,974 | G/A | — | benign |
| rs148433415 | 1:89,657,009 | C/G | — | uncertain significance |
| rs372589831 | 1:89,657,015 | T/C | — | uncertain significance |
| rs769660126 | 1:89,657,123 | C/T | — | uncertain significance |
| rs138876066 | 1:89,657,129 | C/T | — | uncertain significance |
| rs752608414 | 1:89,658,688 | T/A | — | uncertain significance |
| rs1309426405 | 1:89,658,691 | G/A | — | uncertain significance |
| rs757437413 | 1:89,660,985 | C/G | — | uncertain significance |
| rs138693968 | 1:89,660,987 | A/G | — | uncertain significance |
| rs759572977 | 1:89,661,032 | G/C | — | uncertain significance |
| rs768802950 | 1:89,661,045 | G/A | — | uncertain significance |
| rs372003146 | 1:89,662,799 | G/T | — | uncertain significance |
| rs200823724 | 1:89,662,871 | C/T | — | uncertain significance |
| rs1003131946 | 1:89,662,887 | G/T | — | likely benign |
| rs149002014 | 1:89,662,987 | C/A | — | uncertain significance |
| rs1353452805 | 1:89,664,486 | G/A | — | uncertain significance |
| rs1450591918 | 1:89,664,511 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.