GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
Summary
This gene encodes a member of the glycerophosphodiester phosphodiesterase family of enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. The encoded protein is localized to the cytoplasm and concentrates near the perinuclear region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Known Variants10 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2546577484 | 17:57,298,073 | A/C | — | uncertain significance |
| rs547623653 | 17:57,314,673 | G/A | — | — |
| rs746073578 | 17:57,322,788 | G/A | — | uncertain significance |
| rs765102238 | 17:57,322,899 | C/A | — | uncertain significance |
| rs568624610 | 17:57,323,415 | A/T | — | — |
| rs754329008 | 17:57,334,527 | G/C | — | uncertain significance |
| rs763404838 | 17:57,344,435 | C/G | — | uncertain significance |
| rs2546599472 | 17:57,344,525 | A/G | — | uncertain significance |
| rs375237158 | 17:57,348,340 | A/C | — | uncertain significance |
| rs377470665 | 17:57,348,346 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.