GPM6B
glycoprotein M6B
Summary
This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication. This protein may also be involved in osteoblast differentiation. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes Y and 22. [provided by RefSeq, Jan 2016]
Known Variants16 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs36099093 | X:13,794,363 | A/G | — | benign |
| rs757587714 | X:13,794,368 | C/T | — | uncertain significance |
| rs2519042728 | X:13,794,386 | C/T | — | uncertain significance |
| rs1555910377 | X:13,795,465 | G/A | — | likely benign |
| rs141687297 | X:13,795,519 | G/A | — | likely benign |
| rs774122710 | X:13,797,959 | G/C | — | uncertain significance |
| rs200352293 | X:13,797,993 | G/A | — | uncertain significance |
| rs770553728 | X:13,801,500 | C/T | — | uncertain significance |
| rs2519071745 | X:13,801,551 | G/A | — | uncertain significance |
| rs144162602 | X:13,803,769 | C/T | — | likely benign |
| rs769454569 | X:13,835,001 | G/T | — | uncertain significance |
| rs5934135 | X:13,885,784 | C/G | intron variant | — |
| rs7066890 | X:13,892,582 | T/A | — | — |
| rs6528024 | X:13,930,922 | C/T | intron variant | — |
| rs66819623 | X:13,954,397 | C/T | intron variant | — |
| rs66824950 | X:13,954,494 | C/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.