GPR12
G protein-coupled receptor 12
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and intracellular calcium ion homeostasis. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants17 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs539950231 | 13:27,329,170 | A/G | — | — |
| rs1927522 | 13:27,332,836 | G/A | — | benign |
| rs1406583175 | 13:27,332,995 | G/A | — | uncertain significance |
| rs775896560 | 13:27,333,070 | C/G | — | uncertain significance |
| rs774255213 | 13:27,333,239 | G/T | — | uncertain significance |
| rs149004892 | 13:27,333,451 | C/T | — | uncertain significance |
| rs151131193 | 13:27,333,467 | C/T | — | benign |
| rs1484105114 | 13:27,333,586 | A/G | — | uncertain significance |
| rs1379804415 | 13:27,333,624 | A/G | — | uncertain significance |
| rs2500291780 | 13:27,333,637 | C/T | — | uncertain significance |
| rs1303444719 | 13:27,333,652 | A/G | — | uncertain significance |
| rs1884441929 | 13:27,333,660 | A/G | — | uncertain significance |
| rs760020683 | 13:27,333,670 | T/A | — | uncertain significance |
| rs2500292930 | 13:27,333,888 | G/A | — | uncertain significance |
| rs2500293191 | 13:27,333,960 | T/G | — | uncertain significance |
| rs76476101 | 13:27,334,024 | T/C | — | benign |
| rs9581737 | 13:27,334,084 | C/T | — | benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.