GPRC5C
G protein-coupled receptor class C group 5 member C
Summary
The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Known Variants37 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1354301586 | 17:72,428,182 | G/C | — | uncertain significance |
| rs142016992 | 17:72,428,218 | G/A | — | likely benign |
| rs374395462 | 17:72,428,277 | G/C | — | uncertain significance |
| rs548628634 | 17:72,435,942 | G/A | — | uncertain significance |
| rs562285229 | 17:72,435,982 | G/A | — | uncertain significance |
| rs747609002 | 17:72,436,091 | C/T | — | uncertain significance |
| rs80079984 | 17:72,436,120 | A/G | — | benign |
| rs778301166 | 17:72,436,249 | G/A | — | uncertain significance |
| rs1176815451 | 17:72,436,279 | C/T | — | uncertain significance |
| rs367566990 | 17:72,436,340 | A/C | — | uncertain significance |
| rs1229179337 | 17:72,436,369 | C/T | — | uncertain significance |
| rs775751813 | 17:72,436,393 | G/A | — | uncertain significance |
| rs199736709 | 17:72,436,507 | G/A | — | uncertain significance |
| rs2055513324 | 17:72,436,550 | C/G | — | uncertain significance |
| rs371423561 | 17:72,436,630 | C/T | — | uncertain significance |
| rs1443380875 | 17:72,436,657 | A/G | — | uncertain significance |
| rs190174827 | 17:72,436,664 | C/T | — | uncertain significance |
| rs775087365 | 17:72,436,699 | A/C | — | uncertain significance |
| rs1021757248 | 17:72,436,700 | T/C | — | uncertain significance |
| rs374443973 | 17:72,436,855 | G/T | — | uncertain significance |
| rs143305891 | 17:72,436,873 | C/T | — | uncertain significance |
| rs2670824 | 17:72,438,972 | C/G | regulatory region variant | — |
| rs1310127380 | 17:72,439,963 | G/A | — | uncertain significance |
| rs531943666 | 17:72,439,983 | G/A | — | uncertain significance |
| rs754441544 | 17:72,439,990 | A/G | — | uncertain significance |
| rs142708564 | 17:72,440,049 | C/A | — | likely benign |
| rs7225984 | 17:72,440,591 | G/C | — | — |
| rs548471843 | 17:72,442,991 | G/A | — | uncertain significance |
| rs1309107781 | 17:72,443,018 | C/T | — | uncertain significance |
| rs371805436 | 17:72,443,066 | C/T | — | uncertain significance |
| rs773792582 | 17:72,443,088 | C/G | — | uncertain significance |
| rs556337705 | 17:72,443,091 | A/G | — | uncertain significance |
| rs201104752 | 17:72,443,111 | C/T | — | uncertain significance |
| rs760584705 | 17:72,443,112 | C/A | — | uncertain significance |
| rs757207937 | 17:72,443,115 | C/T | — | likely benign |
| rs140956731 | 17:72,443,164 | C/T | — | likely benign |
| rs562054479 | 17:72,446,248 | C/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.