IER3
immediate early response 3
Summary
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008]
Known Variants9 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2536770116 | 6:30,711,723 | G/T | — | uncertain significance |
| rs777479362 | 6:30,711,766 | C/A | — | uncertain significance |
| rs138441333 | 6:30,711,855 | G/A | — | uncertain significance |
| rs894913242 | 6:30,711,907 | T/C | — | likely benign |
| rs201638828 | 6:30,712,202 | C/T | — | uncertain significance |
| rs1310162452 | 6:30,712,207 | C/A | — | uncertain significance |
| rs371952535 | 6:30,712,225 | A/T | — | likely benign |
| rs2536775624 | 6:30,712,259 | T/G | — | uncertain significance |
| rs3130662 | 6:30,713,808 | C/A | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.