IL17D

interleukin 17D

Summary

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]

Known Variants24 total

rsidPosition (GRCh37)AllelesClassClinVar
rs254902280413:21,278,216G/A—uncertain significance
rs91860475213:21,278,217C/T—uncertain significance
rs77849761713:21,278,220G/C—uncertain significance
rs57653980813:21,278,252C/T—likely benign
rs121406027113:21,278,288G/A—uncertain significance
rs101321210513:21,278,336G/C—uncertain significance
rs123999589613:21,278,352G/C—uncertain significance
rs90499022913:21,278,378C/T—uncertain significance
rs100198457613:21,278,394C/T—uncertain significance
rs120946490013:21,278,420T/C—uncertain significance
rs73553913:21,280,034A/Gdownstream gene variant—
rs7403642713:21,285,539C/G——
rs4147655113:21,288,010G/Ccoding sequence variant—
rs135691422113:21,295,785G/C—uncertain significance
rs75237174513:21,295,797T/C—uncertain significance
rs14016106213:21,295,823C/T—likely benign
rs78023842313:21,295,845A/G—uncertain significance
rs14389029313:21,295,850G/C—benign
rs77648276313:21,295,869G/A—uncertain significance
rs37206016913:21,295,921C/G—uncertain significance
rs11204374113:21,296,036C/G—benign
rs14888180313:21,296,037G/C—uncertain significance
rs14697198613:21,296,049G/A—uncertain significance
rs77273432613:21,296,055C/G—uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.