IL17D
interleukin 17D
Summary
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
Known Variants24 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2549022804 | 13:21,278,216 | G/A | — | uncertain significance |
| rs918604752 | 13:21,278,217 | C/T | — | uncertain significance |
| rs778497617 | 13:21,278,220 | G/C | — | uncertain significance |
| rs576539808 | 13:21,278,252 | C/T | — | likely benign |
| rs1214060271 | 13:21,278,288 | G/A | — | uncertain significance |
| rs1013212105 | 13:21,278,336 | G/C | — | uncertain significance |
| rs1239995896 | 13:21,278,352 | G/C | — | uncertain significance |
| rs904990229 | 13:21,278,378 | C/T | — | uncertain significance |
| rs1001984576 | 13:21,278,394 | C/T | — | uncertain significance |
| rs1209464900 | 13:21,278,420 | T/C | — | uncertain significance |
| rs735539 | 13:21,280,034 | A/G | downstream gene variant | — |
| rs74036427 | 13:21,285,539 | C/G | — | — |
| rs41476551 | 13:21,288,010 | G/C | coding sequence variant | — |
| rs1356914221 | 13:21,295,785 | G/C | — | uncertain significance |
| rs752371745 | 13:21,295,797 | T/C | — | uncertain significance |
| rs140161062 | 13:21,295,823 | C/T | — | likely benign |
| rs780238423 | 13:21,295,845 | A/G | — | uncertain significance |
| rs143890293 | 13:21,295,850 | G/C | — | benign |
| rs776482763 | 13:21,295,869 | G/A | — | uncertain significance |
| rs372060169 | 13:21,295,921 | C/G | — | uncertain significance |
| rs112043741 | 13:21,296,036 | C/G | — | benign |
| rs148881803 | 13:21,296,037 | G/C | — | uncertain significance |
| rs146971986 | 13:21,296,049 | G/A | — | uncertain significance |
| rs772734326 | 13:21,296,055 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.