IL17RE
interleukin 17 receptor E
Summary
This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
Known Variants47 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs777105188 | 3:9,944,579 | G/A | — | uncertain significance |
| rs373804985 | 3:9,944,588 | T/C | — | uncertain significance |
| rs377053016 | 3:9,944,619 | G/A | — | uncertain significance |
| rs12492494 | 3:9,944,636 | C/T | — | benign |
| rs147707054 | 3:9,944,671 | G/A | — | uncertain significance |
| rs781399788 | 3:9,944,701 | C/T | — | uncertain significance |
| rs199990414 | 3:9,944,702 | G/A | — | uncertain significance |
| rs771287551 | 3:9,944,710 | C/A | — | uncertain significance |
| rs2469965129 | 3:9,944,723 | C/T | — | uncertain significance |
| rs777885324 | 3:9,945,085 | A/G | — | uncertain significance |
| rs759166537 | 3:9,945,739 | C/T | — | uncertain significance |
| rs755429353 | 3:9,945,782 | G/A | — | uncertain significance |
| rs745494800 | 3:9,946,355 | C/T | — | — |
| rs971780239 | 3:9,948,065 | T/C | — | uncertain significance |
| rs372470651 | 3:9,948,112 | C/A | — | uncertain significance |
| rs1053607809 | 3:9,948,444 | C/T | — | uncertain significance |
| rs368085212 | 3:9,948,519 | C/A | — | uncertain significance |
| rs764951330 | 3:9,948,681 | G/A | — | uncertain significance |
| rs777989851 | 3:9,948,722 | G/A | — | uncertain significance |
| rs7356031 | 3:9,948,774 | A/G | — | benign |
| rs138745343 | 3:9,948,783 | A/T | — | uncertain significance |
| rs2469995898 | 3:9,949,936 | G/A | — | uncertain significance |
| rs753908988 | 3:9,949,948 | T/C | — | uncertain significance |
| rs1298869570 | 3:9,952,555 | C/T | — | uncertain significance |
| rs115354176 | 3:9,952,559 | C/A | — | benign |
| rs777605624 | 3:9,952,581 | A/G | — | uncertain significance |
| rs144937970 | 3:9,952,627 | G/A | missense variant | — |
| rs61743385 | 3:9,952,668 | G/A | — | benign |
| rs2470008019 | 3:9,952,672 | G/C | — | uncertain significance |
| rs767101306 | 3:9,952,678 | C/T | — | uncertain significance |
| rs370860056 | 3:9,952,818 | T/C | — | uncertain significance |
| rs376826050 | 3:9,955,644 | G/A | — | likely benign |
| rs144171626 | 3:9,955,647 | G/A | — | uncertain significance |
| rs376636725 | 3:9,955,690 | G/T | — | uncertain significance |
| rs766884498 | 3:9,956,407 | C/G | — | uncertain significance |
| rs1450815582 | 3:9,956,423 | G/A | — | uncertain significance |
| rs2470033514 | 3:9,956,954 | A/C | — | likely benign |
| rs1452695767 | 3:9,956,958 | C/T | — | uncertain significance |
| rs943882747 | 3:9,956,961 | C/T | — | uncertain significance |
| rs781584427 | 3:9,956,995 | G/A | — | uncertain significance |
| rs2470035319 | 3:9,957,045 | C/T | — | uncertain significance |
| rs779763652 | 3:9,957,184 | C/G | — | uncertain significance |
| rs912461029 | 3:9,957,196 | C/T | — | uncertain significance |
| rs2470038228 | 3:9,957,202 | C/T | — | uncertain significance |
| rs925243817 | 3:9,957,304 | C/T | — | uncertain significance |
| rs1278246905 | 3:9,957,390 | A/T | — | uncertain significance |
| rs774228808 | 3:9,957,441 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.