INPP1
inositol polyphosphate-1-phosphatase
Summary
This gene encodes the enzyme inositol polyphosphate-1-phosphatase, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. [provided by RefSeq, Jul 2008]
Known Variants17 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs4274625 | 2:191,215,035 | A/G | intron variant | — |
| rs770963149 | 2:191,224,884 | C/T | — | uncertain significance |
| rs2067404 | 2:191,224,927 | C/T | — | benign |
| rs1309696944 | 2:191,224,979 | A/T | — | uncertain significance |
| rs2067416 | 2:191,226,742 | A/T | — | — |
| rs768673209 | 2:191,231,455 | G/T | — | uncertain significance |
| rs758183651 | 2:191,231,580 | A/G | — | likely benign |
| rs771754946 | 2:191,233,942 | G/A | — | uncertain significance |
| rs746741158 | 2:191,233,948 | C/T | — | uncertain significance |
| rs1689786838 | 2:191,235,590 | G/C | — | uncertain significance |
| rs766914572 | 2:191,235,617 | T/C | — | uncertain significance |
| rs774250819 | 2:191,235,691 | G/T | — | uncertain significance |
| rs1689792057 | 2:191,235,773 | A/C | — | uncertain significance |
| rs778874532 | 2:191,235,808 | A/C | — | uncertain significance |
| rs369912593 | 2:191,235,868 | A/C | — | uncertain significance |
| rs140741805 | 2:191,235,939 | C/G | — | uncertain significance |
| rs138606587 | 2:191,235,978 | G/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.