KCNK5
potassium two pore domain channel subfamily K member 5
Summary
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport. [provided by RefSeq, Jul 2008]
Known Variants39 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs9462487 | 6:39,158,773 | G/T | — | benign |
| rs141021638 | 6:39,158,841 | T/C | — | uncertain significance |
| rs147451811 | 6:39,158,947 | C/T | — | benign |
| rs779276626 | 6:39,158,959 | C/T | — | uncertain significance |
| rs545915683 | 6:39,158,981 | C/T | — | likely benign |
| rs773970421 | 6:39,158,993 | G/C | — | uncertain significance |
| rs148036963 | 6:39,159,001 | C/T | — | uncertain significance |
| rs934146177 | 6:39,159,025 | G/A | — | uncertain significance |
| rs2480881246 | 6:39,159,040 | C/G | — | uncertain significance |
| rs781338295 | 6:39,159,064 | C/T | — | uncertain significance |
| rs41273124 | 6:39,159,072 | T/A | — | likely benign |
| rs761837668 | 6:39,159,084 | G/A | — | uncertain significance |
| rs139464201 | 6:39,159,112 | C/T | — | uncertain significance |
| rs886586058 | 6:39,159,115 | G/A | — | uncertain significance |
| rs201768235 | 6:39,159,172 | C/T | — | likely benign |
| rs142417837 | 6:39,159,217 | C/G | — | uncertain significance |
| rs748043000 | 6:39,159,218 | G/A | — | likely benign |
| rs1770933868 | 6:39,159,237 | T/C | — | uncertain significance |
| rs142110814 | 6:39,159,304 | C/T | — | uncertain significance |
| rs147772924 | 6:39,159,346 | G/C | — | uncertain significance |
| rs575373077 | 6:39,159,387 | C/T | — | uncertain significance |
| rs2480883060 | 6:39,159,496 | G/A | — | uncertain significance |
| rs781700853 | 6:39,162,038 | C/T | — | uncertain significance |
| rs751933589 | 6:39,162,077 | C/T | — | uncertain significance |
| rs762031149 | 6:39,162,097 | G/A | — | uncertain significance |
| rs1434068869 | 6:39,162,397 | C/G | — | uncertain significance |
| rs199498902 | 6:39,162,417 | G/A | — | uncertain significance |
| rs373094033 | 6:39,162,501 | G/A | — | uncertain significance |
| rs775119102 | 6:39,162,504 | C/T | — | uncertain significance |
| rs1770999660 | 6:39,162,515 | T/C | — | uncertain significance |
| rs1771023951 | 6:39,163,733 | C/T | — | uncertain significance |
| rs2480894145 | 6:39,163,738 | C/A | — | uncertain significance |
| rs568562416 | 6:39,171,709 | C/T | — | — |
| rs10947789 | 6:39,174,922 | T/C | intron variant | — |
| rs10456100 | 6:39,183,470 | C/T | regulatory region variant | — |
| rs537740323 | 6:39,188,297 | A/G | — | — |
| rs6918122 | 6:39,188,691 | C/T | intron variant | — |
| rs2480943916 | 6:39,196,846 | G/T | — | uncertain significance |
| rs758387678 | 6:39,196,847 | A/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.