KCNT2

potassium sodium-activated channel subfamily T member 2

Summary

Enables chloride-activated potassium channel activity and intracellular sodium-activated potassium channel activity. Involved in potassium ion export across plasma membrane. Located in plasma membrane. Implicated in developmental and epileptic encephalopathy 57. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants156 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs760199544	1:196,197,355	C/T	—	likely benign
rs760206396	1:196,197,429	T/G	—	likely benign
rs765518576	1:196,197,442	A/C	—	uncertain significance
rs1488088605	1:196,197,446	G/A	—	uncertain significance
rs1653651798	1:196,197,463	T/C	—	uncertain significance
rs2527605199	1:196,205,123	C/T	—	uncertain significance
rs573616600	1:196,205,140	G/A	—	uncertain significance
rs538439492	1:196,205,162	G/A	—	likely benign
rs1656687729	1:196,227,345	C/T	—	uncertain significance
rs201142057	1:196,227,385	T/G	—	uncertain significance
rs1454847660	1:196,227,416	C/A	—	likely benign
rs1035700995	1:196,227,480	G/A	—	conflicting classifications of pathogenicity
rs991479915	1:196,227,509	A/G	—	uncertain significance
rs2527784043	1:196,227,515	T/G	—	uncertain significance
rs190445712	1:196,227,521	G/A	—	uncertain significance
rs977157	1:196,227,526	A/G	—	benign
rs2527784367	1:196,227,530	C/T	—	uncertain significance
rs748584163	1:196,227,575	T/C	—	likely benign
rs2147780395	1:196,227,582	C/T	—	uncertain significance
rs2527785561	1:196,227,590	T/G	—	uncertain significance
rs375768600	1:196,227,616	T/C	—	likely benign
rs192461268	1:196,239,002	G/A	intron variant	—
rs1646608511	1:196,242,603	A/G	—	uncertain significance
rs886920822	1:196,242,615	G/A	—	likely benign
rs185228317	1:196,249,982	T/C	—	likely benign
rs1214879833	1:196,250,026	G/C	—	uncertain significance
rs2527981182	1:196,250,033	A/G	—	uncertain significance
rs370193320	1:196,250,054	G/T	—	uncertain significance
rs2147868112	1:196,250,069	T/C	—	uncertain significance
rs2527981965	1:196,250,078	G/T	—	uncertain significance
rs2147873696	1:196,251,429	T/C	—	uncertain significance
rs116433080	1:196,254,166	A/G	intron variant	—
rs1659588692	1:196,254,804	C/T	—	uncertain significance
rs2528030641	1:196,254,809	A/C	—	uncertain significance
rs1219046745	1:196,254,810	T/C	—	uncertain significance
rs2147891262	1:196,254,848	C/T	—	uncertain significance
rs142530070	1:196,259,038	G/C	—	benign
rs576561354	1:196,270,909	G/A	—	—
rs60422157	1:196,274,357	G/A	—	benign
rs1661522233	1:196,274,399	C/T	—	uncertain significance
rs2147978587	1:196,274,425	A/C	—	uncertain significance
rs371248112	1:196,274,433	G/A	—	likely benign
rs1662672094	1:196,285,086	T/C	—	uncertain significance
rs748615136	1:196,285,090	G/A	—	likely benign
rs774177783	1:196,288,645	T/G	—	uncertain significance
rs2526677721	1:196,288,653	C/A	—	uncertain significance
rs760245363	1:196,288,656	C/G	—	uncertain significance
rs927345179	1:196,288,679	A/C	—	uncertain significance
rs2526678350	1:196,288,686	C/G	—	uncertain significance
rs115074661	1:196,295,857	A/C	—	uncertain significance
rs1212384684	1:196,295,874	T/C	—	uncertain significance
rs752227943	1:196,295,890	G/A	—	uncertain significance
rs2526804044	1:196,295,904	C/T	—	uncertain significance
rs41304558	1:196,295,914	C/G	—	likely benign
rs1327032306	1:196,295,941	C/T	—	uncertain significance
rs2526807384	1:196,296,000	T/C	—	uncertain significance
rs763718667	1:196,300,316	T/A	—	uncertain significance
rs913490348	1:196,300,396	A/G	—	uncertain significance
rs148371470	1:196,300,412	T/C	intron variant	—
rs760411663	1:196,303,040	T/C	—	uncertain significance
rs2526938479	1:196,303,046	G/A	—	uncertain significance
rs149725107	1:196,303,055	G/A	—	likely benign
rs1475392932	1:196,303,059	A/T	—	uncertain significance
rs760051450	1:196,303,071	C/G	—	uncertain significance
rs2526939507	1:196,303,090	G/A	—	likely benign
rs2526939630	1:196,303,095	G/C	—	uncertain significance
rs140016748	1:196,303,104	T/C	—	likely benign
rs2526942069	1:196,303,170	G/C	—	uncertain significance
rs749770012	1:196,309,509	G/A	—	uncertain significance
rs140538298	1:196,309,524	G/A	—	likely benign
rs1572096837	1:196,309,564	T/A	—	likely pathogenic
rs2527041400	1:196,309,587	G/A	—	likely pathogenic
rs1665510651	1:196,309,615	T/C	—	uncertain significance
rs780602272	1:196,309,627	T/C	—	uncertain significance
rs528303127	1:196,309,633	G/A	—	pathogenic
rs1234933126	1:196,309,635	G/A	—	uncertain significance
rs2527043198	1:196,309,638	C/A	—	uncertain significance
rs2527043511	1:196,309,647	A/G	—	uncertain significance
rs2527044171	1:196,309,665	T/A	—	uncertain significance
rs373639174	1:196,309,672	T/G	—	likely benign
rs200217178	1:196,309,693	C/T	—	likely benign
rs2527045292	1:196,309,695	C/T	—	uncertain significance
rs2527067686	1:196,311,227	G/C	—	uncertain significance
rs1665690526	1:196,311,234	A/G	—	uncertain significance
rs145756671	1:196,311,253	A/G	—	benign
rs1000540819	1:196,311,267	A/T	—	uncertain significance
rs148698179	1:196,311,284	A/G	—	conflicting classifications of pathogenicity
rs141251248	1:196,311,307	G/A	—	likely benign
rs1318859712	1:196,311,310	G/T	—	uncertain significance
rs765937619	1:196,311,311	C/A	—	uncertain significance
rs2527070846	1:196,311,336	G/A	—	uncertain significance
rs758788707	1:196,311,343	C/T	—	likely benign
rs1668677136	1:196,342,312	G/A	—	uncertain significance
rs1189514330	1:196,342,396	G/A	—	uncertain significance
rs16839832	1:196,349,909	G/T	intron variant	—
rs184539630	1:196,366,648	C/T	intron variant	—
rs2527821598	1:196,367,692	C/A	—	uncertain significance
rs1328309959	1:196,367,723	G/A	—	uncertain significance
rs748731106	1:196,367,724	C/T	—	uncertain significance
rs2527823080	1:196,367,756	G/C	—	uncertain significance

Showing 100 of 156 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.