KIF24
kinesin family member 24
Summary
This gene encodes a member of the kinesin superfamily of microtubule-based motor proteins which are involved in the intracellular transport of membranous organelles, protein complexes, and mRNAs. They also play critical roles in mitosis, morphogenesis, and signal transduction. The encoded protein contains an N-terminal sterile alpha motif (SAM) domain and an ATP-binding kinesin motor domain. It binds centriolar coiled coil protein 110 and centrosomal protein 97 and localizes to the mother centriole to regulate ciliogenesis by controlling microtubule polymerization. [provided by RefSeq, Mar 2017]
Known Variants87 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs754116500 | 9:34,254,430 | T/G | — | uncertain significance |
| rs749149971 | 9:34,254,448 | C/T | — | uncertain significance |
| rs2491165049 | 9:34,254,475 | A/G | — | uncertain significance |
| rs140797044 | 9:34,254,496 | T/C | — | uncertain significance |
| rs367826400 | 9:34,255,063 | T/C | — | benign |
| rs2491171645 | 9:34,255,161 | T/C | — | uncertain significance |
| rs2491176866 | 9:34,255,812 | T/C | — | uncertain significance |
| rs76716576 | 9:34,255,823 | C/G | — | benign |
| rs932671041 | 9:34,255,832 | G/A | — | uncertain significance |
| rs1217541049 | 9:34,255,863 | T/G | — | uncertain significance |
| rs41274039 | 9:34,255,988 | A/C | — | benign |
| rs140111978 | 9:34,256,009 | A/G | — | uncertain significance |
| rs755772749 | 9:34,256,022 | T/C | — | uncertain significance |
| rs1587906084 | 9:34,256,028 | T/G | — | likely benign |
| rs781559463 | 9:34,256,069 | G/A | — | uncertain significance |
| rs772376773 | 9:34,256,265 | G/C | — | uncertain significance |
| rs1470276134 | 9:34,256,310 | G/T | — | uncertain significance |
| rs747269713 | 9:34,256,366 | A/G | — | uncertain significance |
| rs140908879 | 9:34,256,402 | G/A | — | likely benign |
| rs758505988 | 9:34,256,405 | G/A | — | uncertain significance |
| rs150397200 | 9:34,256,442 | A/T | — | uncertain significance |
| rs2491184604 | 9:34,256,444 | A/G | — | uncertain significance |
| rs73494718 | 9:34,256,465 | C/A | — | benign |
| rs144807070 | 9:34,256,487 | T/A | — | uncertain significance |
| rs756003155 | 9:34,256,498 | C/T | — | likely benign |
| rs117856906 | 9:34,256,579 | C/T | — | uncertain significance |
| rs116061961 | 9:34,256,584 | A/T | — | benign |
| rs147787588 | 9:34,256,649 | T/A | — | likely benign |
| rs368539542 | 9:34,256,788 | T/C | — | likely benign |
| rs149107818 | 9:34,256,887 | G/A | — | benign |
| rs199561692 | 9:34,256,910 | T/C | — | uncertain significance |
| rs776664861 | 9:34,256,963 | C/T | — | uncertain significance |
| rs775350956 | 9:34,256,984 | T/C | — | uncertain significance |
| rs1173020262 | 9:34,257,048 | C/A | — | uncertain significance |
| rs774105577 | 9:34,257,192 | G/A | — | uncertain significance |
| rs2491194055 | 9:34,257,218 | G/A | — | uncertain significance |
| rs78255362 | 9:34,257,223 | C/T | — | benign |
| rs749406165 | 9:34,257,272 | T/A | — | uncertain significance |
| rs1176570345 | 9:34,257,305 | T/C | — | uncertain significance |
| rs370686946 | 9:34,257,383 | G/A | — | uncertain significance |
| rs770568447 | 9:34,257,471 | C/A | — | uncertain significance |
| rs774950115 | 9:34,257,492 | T/C | — | likely benign |
| rs1422381960 | 9:34,257,509 | A/G | — | uncertain significance |
| rs2491198947 | 9:34,257,608 | G/A | — | uncertain significance |
| rs200178053 | 9:34,257,648 | G/A | — | uncertain significance |
| rs369158262 | 9:34,257,753 | T/C | — | uncertain significance |
| rs376543018 | 9:34,257,759 | G/T | — | uncertain significance |
| rs201469275 | 9:34,257,794 | G/A | — | uncertain significance |
| rs528128260 | 9:34,257,843 | C/A | — | uncertain significance |
| rs139062260 | 9:34,257,908 | G/A | — | benign |
| rs1248671533 | 9:34,257,909 | A/G | — | uncertain significance |
| rs770874834 | 9:34,257,959 | C/G | — | uncertain significance |
| rs535057378 | 9:34,259,601 | C/A | — | uncertain significance |
| rs535585536 | 9:34,259,654 | T/C | — | pathogenic |
| rs143690751 | 9:34,259,667 | A/G | — | uncertain significance |
| rs762287505 | 9:34,269,304 | T/C | — | uncertain significance |
| rs774207912 | 9:34,271,906 | T/A | — | uncertain significance |
| rs1406326273 | 9:34,271,910 | T/G | — | uncertain significance |
| rs749508075 | 9:34,286,665 | T/C | — | uncertain significance |
| rs1157372783 | 9:34,286,673 | A/T | — | uncertain significance |
| rs367662550 | 9:34,286,691 | C/T | — | uncertain significance |
| rs10814091 | 9:34,287,840 | G/A | intron variant | — |
| rs370091940 | 9:34,290,220 | T/C | — | uncertain significance |
| rs201627527 | 9:34,290,286 | T/C | — | uncertain significance |
| rs1836512462 | 9:34,297,086 | A/T | — | uncertain significance |
| rs77040842 | 9:34,306,308 | T/C | — | benign |
| rs369482032 | 9:34,306,332 | T/C | — | uncertain significance |
| rs776926178 | 9:34,306,372 | G/A | — | uncertain significance |
| rs2491472955 | 9:34,306,386 | A/G | — | uncertain significance |
| rs1331775807 | 9:34,310,728 | C/G | — | uncertain significance |
| rs764765032 | 9:34,310,764 | T/C | — | uncertain significance |
| rs2491494864 | 9:34,310,863 | G/C | — | uncertain significance |
| rs1432192801 | 9:34,310,873 | C/T | — | uncertain significance |
| rs2491494961 | 9:34,310,874 | T/A | — | likely benign |
| rs1189548473 | 9:34,310,875 | G/A | — | uncertain significance |
| rs41274845 | 9:34,311,020 | C/T | — | benign |
| rs772997925 | 9:34,311,061 | C/T | — | uncertain significance |
| rs369743252 | 9:34,311,094 | C/A | — | uncertain significance |
| rs375357723 | 9:34,311,119 | G/A | — | uncertain significance |
| rs2491497506 | 9:34,311,125 | G/C | — | uncertain significance |
| rs759827357 | 9:34,311,144 | T/A | — | uncertain significance |
| rs369938636 | 9:34,311,187 | C/T | — | uncertain significance |
| rs111556715 | 9:34,311,194 | G/C | — | uncertain significance |
| rs370883420 | 9:34,311,230 | C/A | — | uncertain significance |
| rs376039012 | 9:34,311,272 | C/G | — | uncertain significance |
| rs771597033 | 9:34,311,317 | A/G | — | uncertain significance |
| rs188915802 | 9:34,318,683 | G/A | coding sequence variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.