KIF3B
kinesin family member 3B
Summary
The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. [provided by RefSeq, Jul 2008]
Known Variants34 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs6119231 | 20:30,864,592 | G/A | upstream gene variant | — |
| rs13036451 | 20:30,879,481 | C/T | intron variant | — |
| rs1472081286 | 20:30,883,898 | C/G | — | — |
| rs781416477 | 20:30,897,629 | C/T | — | uncertain significance |
| rs201066296 | 20:30,897,637 | G/C | — | uncertain significance |
| rs752014273 | 20:30,897,726 | C/T | — | uncertain significance |
| rs538961202 | 20:30,897,740 | C/T | — | uncertain significance |
| rs545536980 | 20:30,897,909 | G/A | — | uncertain significance |
| rs769441232 | 20:30,898,131 | C/T | — | uncertain significance |
| rs28364805 | 20:30,898,167 | T/C | — | uncertain significance |
| rs759626291 | 20:30,898,202 | A/G | — | uncertain significance |
| rs138197776 | 20:30,898,259 | G/A | — | uncertain significance |
| rs2047794498 | 20:30,898,328 | G/C | — | pathogenic |
| rs1246682171 | 20:30,898,332 | G/A | — | uncertain significance |
| rs2515073310 | 20:30,898,398 | C/T | — | uncertain significance |
| rs2515073474 | 20:30,898,478 | C/A | — | uncertain significance |
| rs2047796277 | 20:30,898,612 | A/T | — | association |
| rs2515074014 | 20:30,898,713 | A/G | — | uncertain significance |
| rs775135537 | 20:30,898,802 | G/A | — | uncertain significance |
| rs2515074299 | 20:30,898,825 | G/A | — | likely benign |
| rs201526535 | 20:30,898,899 | T/G | — | uncertain significance |
| rs6058638 | 20:30,900,714 | G/T | intron variant | — |
| rs35786592 | 20:30,904,029 | G/A | — | benign |
| rs778743312 | 20:30,904,388 | A/G | — | uncertain significance |
| rs2047828707 | 20:30,904,391 | T/C | — | pathogenic |
| rs200067481 | 20:30,914,650 | G/A | — | uncertain significance |
| rs369593565 | 20:30,914,674 | A/T | — | uncertain significance |
| rs2515100151 | 20:30,915,429 | A/G | — | uncertain significance |
| rs201378586 | 20:30,915,444 | C/T | — | uncertain significance |
| rs776583931 | 20:30,917,992 | A/G | — | uncertain significance |
| rs370914318 | 20:30,918,119 | C/T | — | uncertain significance |
| rs565907125 | 20:30,919,046 | C/T | — | uncertain significance |
| rs776982402 | 20:30,919,102 | C/T | — | uncertain significance |
| rs867330475 | 20:30,919,103 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.