LCN8
lipocalin 8
Summary
Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Known Variants18 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs371209581 | 9:139,649,740 | C/T | — | uncertain significance |
| rs150773074 | 9:139,649,761 | C/T | — | likely benign |
| rs766977679 | 9:139,649,762 | G/A | — | uncertain significance |
| rs368173889 | 9:139,649,896 | C/T | — | likely benign |
| rs1847162250 | 9:139,649,912 | C/T | — | uncertain significance |
| rs549295739 | 9:139,649,914 | C/T | — | uncertain significance |
| rs567949310 | 9:139,649,933 | C/G | — | uncertain significance |
| rs2490848756 | 9:139,649,958 | C/G | — | uncertain significance |
| rs534280171 | 9:139,650,880 | T/C | regulatory region variant | — |
| rs776118771 | 9:139,651,029 | C/A | — | uncertain significance |
| rs1020161411 | 9:139,651,035 | G/C | — | uncertain significance |
| rs1373714318 | 9:139,651,039 | C/T | — | uncertain significance |
| rs1301057589 | 9:139,651,497 | A/T | — | uncertain significance |
| rs140571672 | 9:139,651,509 | C/T | — | uncertain significance |
| rs370566056 | 9:139,651,524 | C/T | — | uncertain significance |
| rs550554680 | 9:139,651,541 | A/G | — | uncertain significance |
| rs748907314 | 9:139,651,559 | G/A | — | uncertain significance |
| rs768667904 | 9:139,652,366 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.