LDHC

lactate dehydrogenase C

Summary

Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. [provided by RefSeq, Jul 2008]

Known Variants23 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs769545568	11:18,434,271	A/G	—	uncertain significance
rs73436621	11:18,434,301	A/C	—	benign
rs778272077	11:18,434,302	T/C	—	uncertain significance
rs369553713	11:18,434,324	G/C	—	uncertain significance
rs776379979	11:18,436,762	T/C	—	uncertain significance
rs758939071	11:18,436,773	A/G	—	uncertain significance
rs3740713	11:18,451,096	A/C	intron variant	—
rs1848231488	11:18,451,299	C/G	—	uncertain significance
rs2494685821	11:18,451,387	A/G	—	uncertain significance
rs1001797839	11:18,451,389	T/C	—	uncertain significance
rs1848327032	11:18,456,335	C/G	—	uncertain significance
rs778491375	11:18,456,343	A/G	—	uncertain significance
rs2494693416	11:18,456,349	A/G	—	uncertain significance
rs148817816	11:18,456,373	C/T	—	uncertain significance
rs1171190604	11:18,456,395	A/G	—	uncertain significance
rs1454352044	11:18,456,449	G/A	—	uncertain significance
rs771085598	11:18,460,140	A/G	—	uncertain significance
rs181881801	11:18,460,141	C/T	—	uncertain significance
rs2643858	11:18,462,494	T/A	intron variant	—
rs759268494	11:18,467,786	A/G	—	uncertain significance
rs779043876	11:18,467,833	A/G	—	uncertain significance
rs16935432	11:18,470,487	G/A	downstream gene variant	—
rs375667359	11:18,472,511	G/A	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.