LHX2

LIM homeobox 2

Summary

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]

Known Variants23 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs1407632691	9:126,774,688	A/G	—	uncertain significance
rs1859108494	9:126,774,699	C/G	—	uncertain significance
rs757223404	9:126,774,739	A/G	—	uncertain significance
rs7873029	9:126,776,123	C/T	regulatory region variant	—
rs780690752	9:126,776,252	A/G	—	uncertain significance
rs144291200	9:126,776,410	C/T	—	likely benign
rs2540148631	9:126,777,417	C/A	—	uncertain significance
rs370825161	9:126,777,428	C/T	—	likely benign
rs375687666	9:126,777,584	C/A	—	uncertain significance
rs1178079328	9:126,777,655	C/T	—	uncertain significance
rs1859167678	9:126,777,658	C/G	—	uncertain significance
rs1378909150	9:126,777,660	G/C	—	uncertain significance
rs189601606	9:126,777,726	G/A	—	benign
rs1328709712	9:126,777,781	C/T	—	uncertain significance
rs560527359	9:126,783,378	C/T	—	uncertain significance
rs1303464139	9:126,783,392	G/A	—	uncertain significance
rs61734362	9:126,783,415	C/T	—	benign
rs140229756	9:126,783,426	C/A	—	likely benign
rs2075064	9:126,783,847	C/T	intron variant	—
rs917783	9:126,790,607	A/C	downstream gene variant	—
rs138022431	9:126,794,782	G/C	—	likely benign
rs2540163610	9:126,794,814	C/T	—	uncertain significance
rs1247793396	9:126,794,962	A/C	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.