LMAN2
lectin, mannose binding 2
Summary
This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq, Oct 2008]
Known Variants28 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs368637534 | 5:176,759,143 | C/G | — | uncertain significance |
| rs150674852 | 5:176,759,170 | C/T | — | benign |
| rs778210101 | 5:176,759,202 | G/A | — | uncertain significance |
| rs758556309 | 5:176,761,290 | G/C | — | uncertain significance |
| rs200209158 | 5:176,761,362 | A/G | — | uncertain significance |
| rs1266517978 | 5:176,761,382 | C/A | — | uncertain significance |
| rs763454602 | 5:176,764,387 | G/A | — | uncertain significance |
| rs377289965 | 5:176,764,396 | G/C | — | uncertain significance |
| rs376430747 | 5:176,764,414 | G/A | — | uncertain significance |
| rs763732580 | 5:176,764,419 | C/T | — | uncertain significance |
| rs770972790 | 5:176,764,524 | C/T | — | uncertain significance |
| rs2480929603 | 5:176,764,738 | A/G | — | uncertain significance |
| rs746002262 | 5:176,764,784 | G/T | — | uncertain significance |
| rs141477421 | 5:176,765,522 | C/T | — | uncertain significance |
| rs567458399 | 5:176,765,558 | C/T | — | uncertain significance |
| rs116121933 | 5:176,766,869 | G/A | downstream gene variant | — |
| rs146251692 | 5:176,767,441 | G/A | downstream gene variant | — |
| rs187267855 | 5:176,771,763 | C/T | upstream gene variant | — |
| rs4976686 | 5:176,772,736 | G/T | — | — |
| rs4976687 | 5:176,772,737 | C/T | — | — |
| rs752881239 | 5:176,778,256 | T/C | — | uncertain significance |
| rs764703405 | 5:176,778,262 | T/G | — | uncertain significance |
| rs11541336 | 5:176,778,533 | A/G | — | benign |
| rs374068511 | 5:176,778,552 | G/A | — | uncertain significance |
| rs554442231 | 5:176,778,582 | G/C | — | uncertain significance |
| rs201780271 | 5:176,778,613 | C/G | — | uncertain significance |
| rs771411045 | 5:176,778,615 | A/T | — | uncertain significance |
| rs1000474241 | 5:176,778,623 | C/A | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.