LMO3

LIM domain only 3

Summary

The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

Known Variants5 total

rsidPosition (GRCh37)AllelesClassClinVar
rs126519596512:16,704,172G/Auncertain significance
rs96052610012:16,747,088T/Clikely benign
rs1105700512:16,748,721A/Gintron variant
rs76477458812:16,753,761C/Tuncertain significance
rs52739863612:16,753,781T/Cuncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.