LPGAT1
lysophosphatidylglycerol acyltransferase 1
Summary
This gene encodes a member of the lysophospholipid acyltransferase family. The encoded protein catalyzes the reacylation of lysophosphatidylglycerol to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Known Variants10 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs11119805 | 1:211,918,244 | T/A | 3 prime UTR variant | — |
| rs2464565224 | 1:211,923,257 | T/C | — | uncertain significance |
| rs370753583 | 1:211,923,271 | G/C | — | uncertain significance |
| rs141885700 | 1:211,923,290 | C/A | — | uncertain significance |
| rs2464565998 | 1:211,923,377 | G/C | — | uncertain significance |
| rs2464570379 | 1:211,924,371 | T/C | — | uncertain significance |
| rs756507411 | 1:211,924,392 | T/C | — | uncertain significance |
| rs75245874 | 1:211,924,419 | G/A | — | benign |
| rs751219704 | 1:211,956,717 | G/A | — | uncertain significance |
| rs1659203026 | 1:211,966,476 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.