LRRC15
leucine rich repeat containing 15
Summary
Enables several functions, including fibronectin binding activity; laminin binding activity; and protein sequestering activity. Involved in several processes, including host-mediated suppression of symbiont invasion; negative regulation of protein localization to plasma membrane; and receptor-mediated virion attachment to host cell. Located in collagen-containing extracellular matrix and plasma membrane. Is active in apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants54 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs13085139 | 3:194,078,013 | T/G | 3 prime UTR variant | — |
| rs73081778 | 3:194,080,033 | C/A | missense variant | — |
| rs1176483760 | 3:194,080,041 | G/T | — | uncertain significance |
| rs200634682 | 3:194,080,082 | C/G | — | uncertain significance |
| rs372437949 | 3:194,080,098 | C/T | — | likely benign |
| rs141299685 | 3:194,080,161 | C/T | — | uncertain significance |
| rs1476257526 | 3:194,080,178 | A/T | — | uncertain significance |
| rs2473969573 | 3:194,080,179 | T/A | — | uncertain significance |
| rs115511298 | 3:194,080,189 | G/A | — | benign |
| rs116058101 | 3:194,080,324 | A/T | — | benign |
| rs1207085957 | 3:194,080,325 | C/T | — | uncertain significance |
| rs376672212 | 3:194,080,371 | T/G | — | uncertain significance |
| rs547023761 | 3:194,080,404 | C/T | — | uncertain significance |
| rs748028002 | 3:194,080,437 | C/G | — | uncertain significance |
| rs552954426 | 3:194,080,470 | G/A | — | uncertain significance |
| rs750924187 | 3:194,080,517 | C/G | — | uncertain significance |
| rs374623314 | 3:194,080,532 | T/C | — | uncertain significance |
| rs376713863 | 3:194,080,554 | C/T | — | uncertain significance |
| rs961667767 | 3:194,080,611 | C/T | — | uncertain significance |
| rs115042160 | 3:194,080,612 | G/T | — | uncertain significance |
| rs552815580 | 3:194,080,688 | C/T | — | uncertain significance |
| rs745844927 | 3:194,080,690 | G/A | — | likely benign |
| rs1012187849 | 3:194,080,701 | C/T | — | uncertain significance |
| rs763072963 | 3:194,080,719 | C/T | — | uncertain significance |
| rs1281068653 | 3:194,080,865 | T/C | — | uncertain significance |
| rs149970426 | 3:194,080,878 | A/G | — | uncertain significance |
| rs180967725 | 3:194,080,887 | G/A | — | uncertain significance |
| rs370518310 | 3:194,080,904 | C/G | — | uncertain significance |
| rs758976763 | 3:194,080,968 | G/A | — | uncertain significance |
| rs199840768 | 3:194,080,982 | A/G | — | uncertain significance |
| rs763975998 | 3:194,081,091 | G/C | — | uncertain significance |
| rs1713581863 | 3:194,081,122 | A/C | — | uncertain significance |
| rs1304851676 | 3:194,081,132 | A/T | — | uncertain significance |
| rs757589083 | 3:194,081,133 | T/C | — | uncertain significance |
| rs2473971849 | 3:194,081,208 | A/G | — | uncertain significance |
| rs2473971869 | 3:194,081,219 | A/C | — | uncertain significance |
| rs200136252 | 3:194,081,222 | C/T | — | uncertain significance |
| rs2473972009 | 3:194,081,313 | G/C | — | uncertain significance |
| rs201351150 | 3:194,081,336 | G/A | — | uncertain significance |
| rs777651951 | 3:194,081,395 | G/T | — | uncertain significance |
| rs139636767 | 3:194,081,406 | C/A | — | uncertain significance |
| rs748136010 | 3:194,081,430 | C/T | — | uncertain significance |
| rs1247835173 | 3:194,081,462 | C/A | — | uncertain significance |
| rs200640377 | 3:194,081,480 | C/T | — | uncertain significance |
| rs146415750 | 3:194,081,532 | C/T | — | uncertain significance |
| rs746440561 | 3:194,081,561 | G/A | — | uncertain significance |
| rs1713607934 | 3:194,081,600 | A/T | — | uncertain significance |
| rs779111515 | 3:194,081,646 | G/A | — | uncertain significance |
| rs373354505 | 3:194,081,681 | C/A | — | uncertain significance |
| rs750463309 | 3:194,081,712 | C/A | — | uncertain significance |
| rs772760726 | 3:194,081,756 | T/C | — | uncertain significance |
| rs10698992 | 3:194,082,909 | A/G | intron variant | — |
| rs57514363 | 3:194,087,927 | T/G | upstream gene variant | — |
| rs34461611 | 3:194,089,001 | C/T | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.