LRRC23
leucine rich repeat containing 23
Summary
Involved in flagellated sperm motility and radial spoke assembly. Located in cytoplasm and sperm flagellum. Implicated in spermatogenic failure 92. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants19 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1007923 | 12:7,014,107 | T/A | regulatory region variant | — |
| rs781879294 | 12:7,015,024 | C/G | — | uncertain significance |
| rs2542493046 | 12:7,015,058 | T/C | — | uncertain significance |
| rs376384986 | 12:7,015,617 | G/A | — | uncertain significance |
| rs2542496283 | 12:7,015,683 | T/C | — | uncertain significance |
| rs782396222 | 12:7,015,694 | G/A | — | uncertain significance |
| rs781962015 | 12:7,015,701 | G/A | — | uncertain significance |
| rs202194814 | 12:7,015,704 | A/G | — | uncertain significance |
| rs1289377349 | 12:7,015,712 | C/T | — | pathogenic |
| rs782308184 | 12:7,016,508 | G/A | — | uncertain significance |
| rs1555139812 | 12:7,016,610 | G/A | — | pathogenic |
| rs992395774 | 12:7,019,081 | G/A | — | uncertain significance |
| rs782603047 | 12:7,019,121 | G/A | — | uncertain significance |
| rs1290875098 | 12:7,021,902 | T/C | — | uncertain significance |
| rs151056534 | 12:7,021,931 | C/T | — | uncertain significance |
| rs782339082 | 12:7,022,000 | C/T | — | uncertain significance |
| rs782815538 | 12:7,022,019 | A/G | — | uncertain significance |
| rs781848742 | 12:7,022,037 | G/A | — | uncertain significance |
| rs781833414 | 12:7,022,150 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.